Jukka Rantanen
University of Copenhagen
363 Papers
2.6K Citations
Jukka Rantanen is an academic researcher from University of Copenhagen. The author has contributed to research in topics: Chemistry & Crystallization. The author has an hindex of 55, co-authored 341 publications. Previous affiliations of Jukka Rantanen include University of Helsinki & National Research Foundation of South Africa.
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Papers
Near-infrared spectroscopy for cocrystal screening. A comparative study with Raman spectroscopy.
Morten Allesø,Sitaram P. Velaga,Amjad Alhalaweh,Claus Cornett,Morten Arendt Rasmussen,Frans van den Berg,Heidi Lopez de Diego,Jukka Rantanen +7 more
TL;DR: The practical hurdle related to the need for reference mixtures seems to restrict the applicability of NIR spectroscopy in cocrystal screening.
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Strategic funding priorities in the pharmaceutical sciences allied to Quality by Design (QbD) and Process Analytical Technology (PAT).
Buket Aksu,Thomas De Beer,Staffan Folestad,Jarkko Ketolainen,Hans H. Lindén,João A. Lopes,Marcel de Matas,Wim Oostra,Jukka Rantanen,Marco Weimer +9 more
TL;DR: In this position paper, the EUFEPS QbD and PAT Sciences network make recommendations that European industry, academia and health agencies focus attention on delivering step changes in science and technology in a number of key themes.
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Particle size dependence of polymorphism in spray-dried mannitol
TL;DR: Spray-drying of mannitol based formulations can result in variation in the solid state composition ofMannitol as a function of particle size, which may be clinically relevant and underlines the need for proper process control of inhalable dry powder produced by spray-dries.
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Solvent Diversity in Polymorph Screening
Morten Allesø,Franciscus Winfried J van der Berg,Claus Cornett,Flemming Jørgensen,Bent Halling-Sørensen,Heidi Lopez de Diego,Lars Hovgaard,Jaakko Aaltonen,Jukka Rantanen +8 more
TL;DR: It was demonstrated how safety aspects can be considered by labeling a large fraction of the solvents in the SOM with toxicological information, and the SOM was chosen as the visually most convenient way to display the diversity of the 218 Solvents.
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Tailor-made solvents for pharmaceutical use? Experimental and computational approach for determining solubility in deep eutectic solvents (DES).
Henrik Palmelund,Martin Andersson,Camilla J. Asgreen,Ben J. Boyd,Jukka Rantanen,Korbinian Löbmann +5 more
- 31 Oct 2019
TL;DR: The relative increase in solubility found in the experimental data could be well predicted ab initio using COSMO-RS, which may in the future be used to reduce the experimental screening of potential DESs for a given API.
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