Judit Rapp
University of Pécs
14 Papers
20 Citations
Judit Rapp is an academic researcher from University of Pécs. The author has contributed to research in topics: Wnt signaling pathway & Receptor. The author has an hindex of 7, co-authored 13 publications.
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Papers
WNT signaling – lung cancer is no exception
TL;DR: The various effects of activation and inhibition of the WNT signaling pathways are summarized in the context of lung carcinogenesis and the role of WNT ligand transport mechanisms is reviewed.
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Down-Regulation of Canonical and Up-Regulation of Non-Canonical Wnt Signalling in the Carcinogenic Process of Squamous Cell Lung Carcinoma
Domokos Bartis,Domokos Bartis,Veronika Csöngei,Alexander Weich,E. Kiss,Szilvia Barkó,Tamas Kovacs,Monika Avdicevic,Vijay K. D'Souza,Judit Rapp,Krisztian Kvell,László Jakab,Miklos Nyitrai,Miklos Nyitrai,Tamas F. Molnar,David R Thickett,Terézia László,Judit E. Pongracz +17 more
TL;DR: Investigation of molecular events in canonical and non-canonical Wnt signalling during SCC development identified Wnt11 and Wnt5a as regulators of cadherin expression and potentiated relocation of β-catenin to the nucleus as an important step in decreased cellular adhesion.
Cigarette Smoke-Induced Pulmonary Inflammation Becomes Systemic by Circulating Extracellular Vesicles Containing Wnt5a and Inflammatory Cytokines.
D. Feller,József Kun,Istvan Ruzsics,Judit Rapp,Veronika Sárosi,Krisztian Kvell,Zsuzsanna Helyes,Judit E. Pongracz +7 more
TL;DR: It is shown that non-canonical and pro-inflammatory Wnt5a is up-regulated by cigarette smoking with parallel up-regulation of pro- inflammatory cytokines in both mouse and human model systems, demonstrating a potential mechanism for the systemic nature of this crippling disease.
Toll-Like Receptor Mediated Activation of Natural Autoantibody Producing B Cell Subpopulations in an Autoimmune Disease Model.
Szabina Erdő-Bonyár,Judit Rapp,Tünde Minier,Gábor Ráth,József Najbauer,László Czirják,Péter Németh,Timea Berki,Diána Simon +8 more
TL;DR: The results support the role of CD180 in the induction of natural autoantibody production, possibly by NS B cells, and suggest an imbalance between the pathologic and natural autoanalyst production in SSc patients.
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