Juan Wang
Nankai University
13 Papers
11 Citations
Juan Wang is an academic researcher from Nankai University. The author has contributed to research in topics: Cancer & Metastasis. The author has an hindex of 7, co-authored 13 publications.
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Papers
CD44ICD promotes breast cancer stemness via PFKFB4-mediated glucose metabolism.
Ruifang Gao,Dan Li,Jing Xun,Wei Zhou,Jun Li,Juan Wang,Chen Liu,Xiru Li,Wenzhi Shen,Huan Qiao,Dwayne G. Stupack,Na Luo,Na Luo +12 more
TL;DR: It is found that the shortest CD44 isoform ( CD44s) inhibits breast cancer stemness, whereas the cleaved product of CD44 (CD44ICD) promotes breast cancerstemness and therapies that target PFKFB4 (e.g., 5MPN therapy) may lead to improved outcomes for cancer patients.
Fractalkine/CX3CR1 induces apoptosis resistance and proliferation through the activation of the AKT/NF-κB cascade in pancreatic cancer cells.
TL;DR: The function of fractalkine is demonstrated in the activation of the AKT/NF‐κB/p65 signalling cascade and mediation of apoptosis resistance in pancreatic cancer cells, indicating its important role in the tumourigenesis of Pancreatic cancer.
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Inactivation of p38 MAPK contributes to stem cell-like properties of non-small cell lung cancer.
Yan Fang,Juan Wang,Guanwen Wang,Chen Zhou,Peng Wang,Shuangtao Zhao,Shaorong Zhao,Shan Huang,Weijun Su,Weijun Su,Pengling Jiang,Antao Chang,Antao Chang,Rong Xiang,Peiqing Sun,Peiqing Sun +15 more
TL;DR: A novel mechanism by which cancer stem cell properties are acquired and maintained in a cancer cell population is demonstrated, a new function of the p38 pathway is revealed, and a new pathway that can potentially serve as a target for cancer therapies aimed at eliminating CSCs is identified.
Artemin regulates CXCR4 expression to induce migration and invasion in pancreatic cancer cells through activation of NF-κB signaling.
TL;DR: Artemin might be an effective and potent therapeutic target for pancreatic cancer metastasis, especially in perineural invasion, by regulating SDF‐1&agr;/CXCR4 axis.
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•Journal Article
Role of Hyaluronan and Glucose on 4-Methylumbelliferone-inhibited Cell Proliferation in Breast Carcinoma Cells
Rongrong Wang,Wei Zhou,Juan Wang,Yanhua Liu,Yanan Chen,Shan Jiang,Xiaohe Luo,Dwayne G. Stupack,Na Luo +8 more
TL;DR: Increased amounts of hyaluronan or glucose in the tumor microenvironment reduced cellular sensitivity of breast carcinoma cells to 4-MU-inhibited cell proliferation.
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