Juan J. Ronco
University of British Columbia
51 Papers
525 Citations
Juan J. Ronco is an academic researcher from University of British Columbia. The author has contributed to research in topics: Medicine & Intensive care. The author has an hindex of 25, co-authored 49 publications. Previous affiliations of Juan J. Ronco include National Heart Foundation of Australia & St. Paul's Hospital.
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Papers
Intensive versus conventional glucose control in critically ill patients.
Nice-Sugar Study Investigators,Dean R. Chittock,Steve Su,D. Blair,Denise Foster,Rinaldo Bellomo,Deborah J. Cook,Vinay Dhingra,Peter Dodek,Paul C. Hébert,William R. Henderson,Stephane Heritier,Daren K. Heyland,Colin McArthur,Ellen McDonald,Imogen Mitchell,Robyn Norton,J. Potter,Bruce G. Robinson,Juan J. Ronco +19 more
TL;DR: In this large, international, randomized trial, it was found that intensive glucose control increased mortality among adults in the ICU: a blood glucose target of 180 mg or less per deciliter resulted in lower mortality than did a target of 81 to 108 mg perDeciliter.
Ventilation Strategy Using Low Tidal Volumes, Recruitment Maneuvers, and High Positive End-Expiratory Pressure for Acute Lung Injury and Acute Respiratory Distress Syndrome A Randomized Controlled Trial
Maureen O. Meade,Deborah J. Cook,Gordon H. Guyatt,Arthur S. Slutsky,Yaseen M. Arabi,D. James Cooper,Andrew Davies,Qi Zhou,Lehana Thabane,Peggy Austin,Stephen E. Lapinsky,A.T. Baxter,James A. Russell,Yoanna Skrobik,Juan J. Ronco,Thomas E. Stewart +15 more
TL;DR: For patients with acute lung injury and acute respiratory distress syndrome, a multifaceted protocolized ventilation strategy designed to recruit and open the lung resulted in no significant difference in all-cause hospital mortality or barotrauma compared with an established low-tidal-volume protocolized breathing strategy.
Hypoglycemia and risk of death in critically ill patients.
Simon Finfer,Bette Liu,Dean R. Chittock,Robyn Norton,John Myburgh,Colin McArthur,Imogen Mitchell,Denise Foster,Vinay Dhingra,William R. Henderson,Juan J. Ronco,Rinaldo Bellomo,Deborah J. Cook,Ellen McDonald,Peter Dodek,Paul C. Hébert,Daren K. Heyland,Bruce G. Robinson +17 more
TL;DR: In critically ill patients, intensive glucose control leads to moderate and severe hypoglycemia, both of which are associated with an increased risk of death, and the association exhibits a dose-response relationship and is strongest for death from distributive shock.
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A pilot clinical trial of recombinant human angiotensin-converting enzyme 2 in acute respiratory distress syndrome
Akram Khan,Cody Benthin,Brian Zeno,Timothy E Albertson,John H. Boyd,Jason D. Christie,Richard I. Hall,Germain Poirier,Juan J. Ronco,Mark Tidswell,Kelly Hardes,William Powley,Tracey J. Wright,Sarah Siederer,David Fairman,David A. Lipson,David A. Lipson,Andrew I. Bayliffe,Aili L. Lazaar,Aili L. Lazaar +19 more
TL;DR: GSK2586881 was well-tolerated in patients with ARDS, and the rapid modulation of RAS peptides suggests target engagement, although the study was not powered to detect changes in acute physiology or clinical outcomes.
Identification of the Critical Oxygen Delivery for Anaerobic Metabolism in Critically III Septic and Nonseptic Humans
Juan J. Ronco,John C. Fenwick,Martin Tweeddale,Barry Wiggs,Phang Pt,D. J. Cooper,K F Cunningham,James A. Russell,Keith R. Walley +8 more
TL;DR: The critical oxygen delivery threshold for anaerobic metabolism was identified from the biphasic relationship between O2 delivery and O2 consumption in individual humans and is considerably lower than previously reported in humans with the use of pooled group data.
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