Joy Simpson
National University of Ireland, Galway
5 Papers
Joy Simpson is an academic researcher from National University of Ireland, Galway. The author has contributed to research in topics: Elevated plus maze & Behavioural despair test. The author has an hindex of 5, co-authored 5 publications.
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Papers
The impact of environmental enrichment in laboratory rats--behavioural and neurochemical aspects.
Joy Simpson,John P. Kelly +1 more
TL;DR: The findings summarised in the present review show the range of EE protocols employed and their effects in tests of activity, learning and affect, as well neurochemical effects which mediate enhanced plasticity in the brain.
472
An investigation of whether there are sex differences in certain behavioural and neurochemical parameters in the rat.
Joy Simpson,John P. Kelly +1 more
TL;DR: The effects of sex on tests of depression- and anxiety-like symptoms, learning and memory, and responses to stress in rats are outlined and sexual dimorphisms in monoamine neurotransmitter and neurotrophic factor levels, neurogenesis and plasticity, and responsiveness to drugs of abuse are reviewed.
131
Sex differences in baseline and drug-induced behavioural responses in classical behavioural tests.
TL;DR: It is demonstrated that male and female rats respond differently to psychotropic drugs, and behavioural tests must be designed to account for sex differences in baseline behaviours to allow for unambiguous extrapolation of the results.
113
Effect of early life housing manipulation on baseline and drug-induced behavioural responses on neurochemistry in the male rat
TL;DR: The results suggest that post-weaning enrichment had no significant effect on baseline behaviours or monoamine and BDNF levels, thus it is suitable to implement as a commonplace husbandry practice, however, caution must be taken when investigating responsiveness to psychotropic drugs.
26
The effects of isolated and enriched housing conditions on baseline and drug-induced behavioural responses in the male rat.
Joy Simpson,John P. Kelly +1 more
TL;DR: It is concluded that environmental manipulation can vary along a continuum and its intensity may be crucial to observable effects in behavioural pharmacological tests in the rat.