Joy L. Ware
Duke University
12 Papers
130 Citations
Joy L. Ware is an academic researcher from Duke University. The author has contributed to research in topics: Antigen & Antibody. The author has an hindex of 8, co-authored 12 publications. Previous affiliations of Joy L. Ware include United States Department of Veterans Affairs.
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Papers
Spontaneous metastasis of cells of the human prostate carcinoma cell line PC-3 in athymic nude mice.
TL;DR: Observed spontaneous metastasis and extensive invasiveness in athymic nude mice injected with human prostatic carcinoma cells of the PC-3 line or heterotransplants of nude mouse supported PC- 3 tumor provide the foundation for a study of the relationship between prostate carcinoma cell characteristics and lymphatic metastasis in the nude mouse.
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•Journal Article
Evidence for a novel hybrid immunotoxin recognizing ricin A-chain by one antigen-combining site and a prostate-restricted antigen by the remaining antigen-combining site: potential for immunotherapy.
TL;DR: It is demonstrated that the MAB population secreted by the second-generation hybridoma can be physicochemically separated into distinct populations exhibiting differential binding to the cultured prostatic carcinoma cell surface and to RAC immobilized in a solid phase.
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Monoclonal antibodies to different epitopes on a prostate tumor-associated antigen. Implications for immunotherapy.
Karen S. Webb,Joy L. Ware,Susanne F. Parks,Susanne F. Parks,William H. Briner,David F. Paulson,David F. Paulson +6 more
TL;DR: In this paper, the p54 antigen has been characterized with regard to tissue distribution using αPro3 and αPro5 monoclonal antibody and sequential immunoprecipitation experiments.
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Characterization of prostate-tissue-directed monoclonal antibody, alpha-Pro 13.
Karen S. Webb,David F. Paulson,David F. Paulson,Susanne F. Parks,Susanne F. Parks,Francis L. Tuck,Philip J. Walther,Philip J. Walther,Joy L. Ware +8 more
TL;DR: The α-Pro 13-secreting hybridoma was produced by immunizing mice with an equal mixture of PC-3, DU145, and LNCaP established prostatic carcinoma cell lines and showed preferential binding to the ductal epithelium of prostate tissue; immunoperoxidase evaluation indicates a considerable heterogeneity of staining of ductalhelial cells.
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