Joy Armistead
University of Cologne
4 Papers
1 Citations
Joy Armistead is an academic researcher from University of Cologne. The author has contributed to research in topics: DNA damage & Poly ADP ribose polymerase. The author has an hindex of 2, co-authored 4 publications.
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Papers
Hemicentin-1 is an essential extracellular matrix component of the dermal-epidermal and myotendinous junctions.
Daniela Welcker,Cornelia Stein,Natália Martins Feitosa,Natália Martins Feitosa,Joy Armistead,Jin-Li Zhang,Steffen Lütke,André Kleinridders,André Kleinridders,Jens C. Brüning,Jens C. Brüning,Sabine A. Eming,Gerhard Sengle,Anja Niehoff,Anja Niehoff,Wilhelm Bloch,Matthias Hammerschmidt +16 more
TL;DR: Transmission electron microscopy revealed ultrastructural basement membrane (BM) alterations at the DEJ and MTJ of Hmcn1-/-mice, pointing to a thus far unknown role of HMCn1 for BM and connective tissue boundary integrity.
Entosis and apical cell extrusion constitute a tumor-suppressive mechanism downstream of Matriptase.
TL;DR: The mechanisms underlying the double face of Matriptase function in vivo are elucidated and the potential use of combinatorial carcinoma treatments when such double-face mechanisms are involved is revealed.
NAMPT-derived NAD+ fuels PARP1 to promote skin inflammation through parthanatos
Francisco J. Martínez-Morcillo,Joaquín Cantón-Sandoval,Francisco J. Martínez-Navarro,Isabel Cabas,Idoya Martínez-Vicente,Joy Armistead,Julia Hatzold,Azucena López-Muñoz,Teresa Martínez-Menchón,Raúl Corbalán-Vélez,Jesús Lacal,Matthias Hammerschmidt,José C. García-Borrón,Alfonsa García-Ayala,María L. Cayuela,Ana B. Pérez-Oliva,Diana García-Moreno,Victoriano Mulero +17 more
TL;DR: In this article, the rate-limiting enzyme in the salvage pathway of NAD+ biosynthesis, reduced oxidative stress, inflammation, and keratinocyte DNA damage, hyperproliferation and cell death in zebrafish models of chronic skin inflammation.
NAMPT-derived NAD+ fuels PARP1 to promote skin inflammation through parthanatos cell death.
Francisco J. Martínez-Morcillo,Joaquín Cantón-Sandoval,Francisco J. Martínez-Navarro,Isabel Cabas,Idoya Martínez-Vicente,Joy Armistead,Julia Hatzold,Azucena López-Muñoz,Teresa Martínez-Menchón,Raúl Corbalán-Vélez,Jesús Lacal,Matthias Hammerschmidt,José C. García-Borrón,Alfonsa García-Ayala,María L. Cayuela,Ana B. Pérez-Oliva,Diana García-Moreno,Victoriano Mulero +17 more
TL;DR: In this article, the rate-limiting enzyme in the salvage pathway of NAD+ biosynthesis, reduced oxidative stress, inflammation, and keratinocyte DNA damage, hyperproliferation, and cell death in zebrafish models of chronic skin inflammation, while all these effects were reversed by NAD+ supplementation.