Joseph Shaw
University of Manchester
8 Papers
1 Citations
Joseph Shaw is an academic researcher from University of Manchester. The author has contributed to research in topics: Medicine & Endometrial cancer. The author has an hindex of 3, co-authored 6 publications.
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Papers
PRE-surgical Metformin In Uterine Malignancy (PREMIUM): a Multi-Center, Randomized Double-Blind, Placebo-Controlled Phase III Trial.
Sarah Kitson,Zoe Maskell,Vanitha N Sivalingam,Jennifer L. Allen,S Ali,S Ali,Sean Burns,Kyle Gilmour,Rahamatulla Latheef,Richard J Slade,Philip W. Pemberton,Joseph Shaw,W David J Ryder,Henry C Kitchener,Emma J Crosbie,Emma J Crosbie +15 more
TL;DR: Short-term treatment with standard diabetic doses of metformin does not reduce tumor proliferation in women with endometrioid endometrial cancer awaiting hysterectomy and casts doubt on its potential application in the primary and adjuvant treatment settings.
Cutaneous pleomorphic adenoma of the periocular region - a case series.
Micheal A. O’Rourke,Paul S. Cannon,Joseph Shaw,Luciane C Irion,Penelope A McKelvie,Alan A McNab +5 more
TL;DR: The clinical features and outcomes in three cases of pleomorphic adenoma with two at the medial canthus (including one recurrence) and one in the brow region are described.
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A palaeoenvironmental record of the Southern Hemisphere last glacial maximum from the Mount Cass loess section, North Canterbury, Aotearoa/New Zealand
Peter C. Almond,Sándor Gulyás,Pál Sümegi,Balázs P. Sümegi,S. J. Covey-Crump,Merren Jones,Joseph Shaw,Andrew Parker +7 more
TL;DR: The authors reconstructs aspects of palaeoenvironment at high resolution through 25 to 21 cal ka BP using radiocarbon ages of carboniferous loess in North Canterbury, eastern South Island, New Zealand.
5
Multi-maintenance olaparib therapy in relapsed, germline BRCA1/2-mutant high-grade serous ovarian cancer (MOLTO): a phase II trial.
Robert D. Morgan,Andrew R Clamp,Daniel J. White,Marcus J Price,George J Burghel,W. D. J. Ryder,Reem D Mahmood,Alexander D Murphy,Jurjees Hasan,Claire Mitchell,Zena Salih,Chelsey Wheeler,Emma Buckley,Joanna Truelove,Georgia King,Yasmina Ainaoui,Sanjeev S. Bhaskar,Joseph Shaw,D. Gareth Evans,Bedirhan Kilerci,Simon P. Pearce,Ged Brady,Caroline Dive,James P B O'Connor,Andrew J Wallace,Dominic G. Rothwell,Richard J. Edmondson,Gordon C Jayson +27 more
TL;DR: In this paper , a single maintenance course of a poly(ADP-ribose) polymerase inhibitor (PARPi) improves progression-free survival (PFS) in germline BRCA1/2-mutant high-grade serous ovarian cancer (gBRCAm-HGSOC).
3
Pre-Surgical Metformin in Uterine Malignancy (Premium): A Multi-Centre, Randomised Double-Blind, Placebo-Controlled Phase 3 Trial
Sarah Kitson,Zoe Maskell,Vanitha N Sivalingam,Jennifer L. Allen,Saad Ali,Saad Ali,Sean Burns,Kyle Gilmour,Rahamatulla Latheef,Richard J Slade,Phil Pemberton,Joseph Shaw,W David J Ryder,Henry C Kitchener,Henry C Kitchener,Emma J Crosbie +15 more
TL;DR: This paper showed that short-term treatment with standard diabetic doses of metformin does not reduce tumour proliferation in women with endometrial cancer awaiting hysterectomy and cast doubt on its potential application in the primary and adjuvant treatment settings.
2