Joseph P. Comunale
Cornell University
31 Papers
59 Citations
Joseph P. Comunale is an academic researcher from Cornell University. The author has contributed to research in topics: Medicine & Quantitative susceptibility mapping. The author has an hindex of 13, co-authored 30 publications. Previous affiliations of Joseph P. Comunale include Kyung Hee University & Pennsylvania Hospital.
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Papers
Quantitative Susceptibility Mapping of Multiple Sclerosis Lesions at Various Ages
Weiwei Chen,Susan A. Gauthier,Ajay Gupta,Joseph P. Comunale,Tian Liu,Shuai Wang,Mengchao Pei,David Pitt,Yi Wang +8 more
TL;DR: Magnetic susceptibility of MS lesions increased rapidly as it changed from enhanced to nonenhanced, it attained a high susceptibility value relative to NAWM during its initial few years, and it gradually dissipated back to susceptibility similar to that of NAWM as it aged, which may provide new insight into pathophysiologic features ofMS lesions.
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Diagnostic accuracy of CT angiography and CT perfusion for cerebral vasospasm: a meta-analysis.
Edward Greenberg,Rachel Gold,Melissa Reichman,Majnu John,Jana Ivanidze,A.M. Edwards,Carl E. Johnson,Joseph P. Comunale,Pina C. Sanelli +8 more
TL;DR: The high diagnostic accuracy determined for both CTA and CTP in this meta-analysis suggests that they are potentially valuable techniques for vasospasm diagnosis in ASAH.
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Quantitative Susceptibility Mapping and R2* Measured Changes during White Matter Lesion Development in Multiple Sclerosis: Myelin Breakdown, Myelin Debris Degradation and Removal, and Iron Accumulation
Yan Zhang,Susan A. Gauthier,Ajay Gupta,Weiwei Chen,Joseph P. Comunale,Gloria C. Chiang,D. Zhou,Gulce Askin,Wenzhen Zhu,David Pitt,Yi Wang +10 more
TL;DR: The authors characterized lesion changes on quantitative susceptibility mapping and R2* at various gadoliniumenhancement stages (nodular, shell-like, nonenhancing) in 64 patients with multiple sclerosis with different enhancing patterns in white matter lesions and found that early active MS lesions with nodular enhancement show R1* decrease but no quantitative susceptibility mapped change, reflecting myelin breakdown.
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Comparison of CT Perfusion and Digital Subtraction Angiography in the Evaluation of Delayed Cerebral Ischemia
Ronan P. Killeen,Alvin I. Mushlin,Carl E. Johnson,Joseph P. Comunale,Apostolos John Tsiouris,Holly Delaney,Allison Dunning,Pina C. Sanelli +7 more
TL;DR: CTP and DSA have similar test characteristics and Bayesian analysis for determining DCI in A-SAH patients and a significant difference in cerebral blood flow values was revealed.
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•Journal Article
Neuroimaging of Cerebrovascular Disease in the Aging Brain
Ajay Gupta,Sreejit Nair,Andrew D. Schweitzer,Sirish Kishore,Carl E. Johnson,Joseph P. Comunale,Apostolos John Tsiouris,Pina C. Sanelli +7 more
TL;DR: Some of the pathophysiologic mechanisms in the aging brain and cerebral vasculature and the related structural abnormalities detectable on neuroimaging are reviewed, including evaluation of age-related white matter changes, atherosclerosis of the cerebral Vasculature, and cerebral infarction.
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