Joseph Balowski
University of North Carolina at Chapel Hill
5 Papers
13 Citations
Joseph Balowski is an academic researcher from University of North Carolina at Chapel Hill. The author has contributed to research in topics: Gene & Enhancer. The author has an hindex of 4, co-authored 4 publications.
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Papers
Micro total analysis systems for cell biology and biochemical assays.
Michelle L. Kovarik,Philip C. Gach,Douglas M. Ornoff,Yuli Wang,Joseph Balowski,Lila Farrag,Nancy L. Allbritton +6 more
TL;DR: Application of µTAS in all of these areas continues to be highly interdisciplinary, utilizing techniques and strategies from almost every scientific field, and insures continued relevance to the biological community as well as a bright future.
A high-throughput platform for stem cell niche co-cultures and downstream gene expression analysis
Adam D. Gracz,Ian A. Williamson,Kyle C. Roche,Michael J. Johnston,Fengchao Wang,Yuli Wang,Peter J. Attayek,Joseph Balowski,Xiao Fu Liu,Ryan J. Laurenza,Liam T. Gaynor,Christopher E. Sims,Joseph A. Galanko,Linheng Li,Nancy L. Allbritton,Scott T. Magness +15 more
TL;DR: A ‘microraft array’ (MRA) is described that facilitates high-throughput clonogenic culture and computational identification of single intestinal stem cells (ISCs) and niche cells and uses MRAs to demonstrate that Paneth cells, a known ISC niche component, enhance organoid formation in a contact-dependent manner.
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Benchtop micromolding of polystyrene by soft lithography.
Yuli Wang,Joseph Balowski,Colleen Phillips,Ryan Phillips,Christopher E. Sims,Nancy L. Allbritton +5 more
TL;DR: Polystyrene was micromolded into two different microarray formats, microwells and microposts, for segregation and tracking of non-adherent and adherent cells, respectively, making it an alternative material to PDMS and suitable for building lab-on-a-chip devices by soft lithography methods.
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Identification of enhancer regulatory elements that direct epicardial gene expression during zebrafish heart regeneration.
Yingxi Cao,Yu Xia,Joseph Balowski,Jianhong Ou,Lingyun Song,Alexias Safi,Timothy Curtis,Gregory E. Crawford,Kenneth D. Poss,Jingli Cao +9 more
TL;DR: This study provides a new resource and principles for understanding the regulation of epicardial genetic programs during heart regeneration through tissue regeneration enhancer elements (TREEs) linked to a regeneration gene.
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Fabrication of 3D Microstructures from Interactions of Immiscible Liquids with a Structured Surface
TL;DR: A new lithography technique is presented that exploits the interactions of immiscible liquids with a structured surface and easily produces curved and/or multi-level structures out of a variety of photoactive and non-photoactive materials.