Jose G. Guillem
Memorial Sloan Kettering Cancer Center
353 Papers
4.8K Citations
Jose G. Guillem is an academic researcher from Memorial Sloan Kettering Cancer Center. The author has contributed to research in topics: Colorectal cancer & Medicine. The author has an hindex of 91, co-authored 342 publications. Previous affiliations of Jose G. Guillem include Beth Israel Medical Center & Cleveland Clinic.
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Papers
Neoadjuvant Chemotherapy First, Followed by Chemoradiation and Then Surgery, in the Management of Locally Advanced Rectal Cancer
Andrea Cercek,Karyn A. Goodman,Carla Hajj,Emily Weisberger,Neil H. Segal,Diane Reidy-Lagunes,Zsofia K. Stadler,Abraham J. Wu,Martin R. Weiser,Philip B. Paty,Jose G. Guillem,Garrett M. Nash,Larissa K. Temple,Julio Garcia-Aguilar,Leonard B. Saltz +14 more
TL;DR: FOLFOX and chemoradiation before planned TME results in tumor regression, a high rate of delivery of planned therapy, and a substantial rate of pathCRs, and offers a good platform for nonoperative management in select patients.
Association of Preoperative and Postoperative Serum Carcinoembryonic Antigen and Colon Cancer Outcome.
Tsuyoshi Konishi,Tsuyoshi Konishi,Yoshifumi Shimada,Yoshifumi Shimada,Meier Hsu,Lauren Tufts,Rosa M Jimenez-Rodriguez,Andrea Cercek,Rona Yaeger,Leonard B. Saltz,J. Joshua Smith,Garrett M. Nash,Jose G. Guillem,Philip B. Paty,Julio Garcia-Aguilar,Mithat Gonen,Martin R. Weiser +16 more
TL;DR: Routine measurement of postoperative, rather than preoperative, CEA is warranted because patients with elevated postoperative CEA are at increased risk for recurrence, especially within the first 12 months after surgery.
Patterns of morphologic alteration in residual rectal carcinoma following preoperative chemoradiation and their association with long-term outcome.
Jinru Shia,Jose G. Guillem,Harvey G. Moore,Satish K. Tickoo,Satish K. Tickoo,Jing Qin,Leyo Ruo,Arief A. Suriawinata,Arief A. Suriawinata,Philip B. Paty,Bruce D. Minsky,Martin R. Weiser,Larissa K. Temple,W. Douglas Wong,David S. Klimstra +14 more
TL;DR: This study represents the first detailed morphologic assessment of rectal carcinomas that have been subjected to long course preoperative RT and chemotherapy and demonstrates distinct morphologic features in treated rectal cancers that are prognostically relevant.
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Preoperative 5-FU, low-dose leucovorin, and radiation therapy for locally advanced and unresectable rectal cancer
Bruce D. Minsky,Alfred M. Cohen,Warren E. Enker,Leonard B. Saltz,Jose G. Guillem,Philip B. Paty,David P. Kelsen,Nancy E. Kemeny,David H. Ilson,Joanne Bass,John A. Conti +10 more
TL;DR: In patients with locally advanced and unresectable rectal cancer, the benefit of downstaging on local control is greatest in patients who achieve a pathologic complete response.
190
Prospective assessment of primary rectal cancer response to preoperative radiation and chemotherapy using 18-fluorodeoxyglucose positron emission tomography.
Jose G. Guillem,Jorge Puig La Calle,Tim Akhurst,Satish K. Tickoo,Leyo Ruo,Bruce D. Minsky,Marc J. Gollub,David S. Klimstra,Madhu Mazumdar,Philip B. Paty,Homer A. Macapinlac,Henry Yeung,Leonard B. Saltz,Ronald D. Finn,Yusef Erdi,John L. Humm,Alfred M. Cohen,Steven M. Larson +17 more
TL;DR: In this paper, a prospective study was conducted to determine the ability of fluorine-18 fluorodeoxyglucose positron emission tomography to assess extent of pathologically confirmed rectal cancer response to preoperative radiation and 5-fluorouracil-based chemotherapy.
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