Joris Vandenbempt
4 Papers
Joris Vandenbempt is an academic researcher. The author has contributed to research in topics: Excitatory postsynaptic potential & Hippocampal formation. The author has co-authored 1 publications.
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Papers
Early alterations in the MCH system link aberrant neuronal activity and sleep disturbances in a mouse model of Alzheimer’s disease
Sara Calafate,Gökhan Özturan,Nicola Thrupp,Jeroen Vanderlinden,Luísa Santa-Marinha,Rafaela Morais-Ribeiro,Antonella Ruggiero,Ivan Bozic,Thomas Rusterholz,Wei Ting Chen,Mark Fiers,Ashley Lu,Ine Vlaeminck,Eline Creemers,Katleen Craessaerts,Joris Vandenbempt,Luuk van Boekholdt,Suresh Poovathingal,Kristofer Davie,Dietmar Rudolf Thal,Keimpe D. Wierda,Tiago Gil Oliveira,Inna Slutsky,Antoine Roger Adamantidis,Bart De Strooper,Joris de Wit +25 more
TL;DR: In this article , homeostatic mechanisms transiently counteract the increased excitatory drive to CA1 neurons in App NL-G-F mice, but that this mechanism fails in older mice.
A postsynaptic GPR158-PLCXD2 complex controls spine apparatus abundance and dendritic spine maturation.
Ben Verpoort,Luísa Amado,Jeroen Vandensteen,Elke Leysen,Dan Dascenco,Joris Vandenbempt,Irma Lemmens,J. Wauman,Kristel M. Vennekens,Abril Escamilla-Ayala,Ana Cristina Nogueira Freitas,Thomas Voets,Sebastian Munck,Jan Tavernier,Keimpe D. Wierda,Joris de Wit +15 more
Cell-surface receptor-mediated regulation of synaptic organelle distribution controls dendritic spine maturation
Ben Verpoort,Luísa Amado,Jeroen Vandensteen,Elke Leysen,Dan Dascenco,Joris Vandenbempt,Irma Lemmens,J. Wauman,Kristel M. Vennekens,Abril Escamilla-Ayala,Ana Cristina Nogueira Freitas,Thomas Voets,Sebastian Munck,Jan Tavernier,Joris de Wit +14 more
TL;DR: Cell-surface receptor-mediated regulation of synaptic organelle distribution controls dendritic spine maturation by modulating the local lipid microenvironment.
A dynamic gene regulatory code drives synaptic development of hippocampal granule cells
Blanca Lorente-Echeverría,Danie Daaboul,Jeroen Vandensteen,Gabriele Marcassa,Willem Naert,Joris Vandenbempt,Elke Leysen,Malou Reverendo,Ine Vlaeminck,Lise Vervloessem,Jochen Lamote,Suresh Poovathingal,Kristofer Davie,Keimpe D. Wierda,Dan Dascenco,Stein Aerts,Joris de Wit +16 more
TL;DR: Researchers reconstructed gene regulatory networks in hippocampal granule cells, revealing a dynamic code that drives synaptic development through sequential regulations, identifying key transcription factors and target genes involved in cell morphogenesis, synapse organization, and plasticity.