Jörg Meyer
Merck & Co.
12 Papers
275 Citations
Jörg Meyer is an academic researcher from Merck & Co.. The author has contributed to research in topics: Cell adhesion molecule & Extracellular matrix. The author has an hindex of 7, co-authored 12 publications. Previous affiliations of Jörg Meyer include Biomet.
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Papers
Surface coating with cyclic RGD peptides stimulates osteoblast adhesion and proliferation as well as bone formation.
Martin Kantlehner,Patricia Schaffner,Dirk Finsinger,Jörg Meyer,Alfred Jonczyk,Beate Diefenbach,Berthold Nies,Günter Hölzemann,Simon L. Goodman,Horst Kessler +9 more
TL;DR: In vivo studies show that peptide‐coated PMMA pellets implanted into the patella groove of rabbits are integrated into the regenerating bone tissue faster and more strongly than uncoated pellets.
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Function of linear and cyclic RGD-containing peptides in osteoprogenitor cells adhesion process.
TL;DR: The results suggest the importance of sequence, structure and conformation of the peptide, which may play a crucial function in the ligand/receptor interaction and/or in the stability of the interaction.
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Selective RGD-Mediated Adhesion of Osteoblasts at Surfaces of Implants.
Martin Kantlehner,Dirk Finsinger,Jörg Meyer,Patricia Schaffner,Alfred Jonczyk,Beate Diefenbach,Berthold Nies,Horst Kessler +7 more
TL;DR: A new procedure is shown which is based on covalent linking of a highly selective RGD peptide to a poly(methyl methacrylate) (PMMA) material, which very effectively bind to the treated surface and are stimulated to proliferate.
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Induced tissue integration of bone implants by coating with bone selective RGD-peptides in vitro and in vivo studies.
Patricia Schaffner,Jörg Meyer,M. Dard,R Wenz,Berthold Nies,Sophie Verrier,H. Kessler,M. Kantlehner +7 more
TL;DR: Implant surfaces biologically functionalized with arginine-glycine-aspartic acid (RGD) peptides, a class of cellular adhesion factors, are described in this paper and show the capability to bind cultured osteoblasts in high levels and show high proliferation rates in vitro.
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Tools for tissue engineering of mineralized oral structures
TL;DR: The experimental use of cyclic RGD peptides grafted on polymethylmethacrylate to improve osteoblast adhesion is reported on and the potential advantage of immobilizing and incorporating collagen I on titanium implant surfaces is shown.
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