Jörg Breitfeld
Federal Institute for Drugs and Medical Devices
4 Papers
25 Citations
Jörg Breitfeld is an academic researcher from Federal Institute for Drugs and Medical Devices. The author has contributed to research in topics: Gene expression & Amygdala. The author has an hindex of 3, co-authored 4 publications.
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Papers
Gene expression and proliferation biomarkers for antidepressant treatment resistance.
Jörg Breitfeld,Catharina Scholl,Michael Steffens,Gonzalo Laje,Julia C. Stingl,Julia C. Stingl +5 more
TL;DR: In vitro cell proliferation testing may serve as functional biomarker for individual neuroplasticity effects of antidepressants in patients from first-line therapy responders and LCLs from treatment-resistant patients.
Proliferation rates and gene expression profiles in human lymphoblastoid cell lines from patients with depression characterized in response to antidepressant drug therapy.
Jörg Breitfeld,Catharina Scholl,Michael Steffens,Kerstin Brandenburg,Kristina Probst-Schendzielorz,O Efimkina,David Gurwitz,Marcus Ising,Florian Holsboer,Susanne Lucae,Julia C. Stingl,Julia C. Stingl +11 more
TL;DR: Potential gene expression biomarkers eventually being useful as baseline predictors or as longitudinal targets in antidepressant therapy are identified.
Repeated fMRI in measuring the activation of the amygdala without habituation when viewing faces displaying negative emotions.
Jennifer Spohrs,Julia E. Bosch,Lisa Dommes,Petra Beschoner,Julia C. Stingl,Franziska Geiser,Katharina L. Schneider,Jörg Breitfeld,Roberto Viviani,Roberto Viviani +9 more
TL;DR: Investigating amygdala activation in healthy participants exposed to displays of emotional facial expressions in a sample of N = 31 individuals assessed twice in an interval of three weeks found no habituation could be detected, suggesting the validity of this imaging assay in repeated assessments of amygdalar reactivity.
Interferon-beta-induced changes in neuroimaging phenotypes of appetitive motivation and reactivity to emotional salience.
Christoph Coch,Roberto Viviani,Jörg Breitfeld,Katrin Münzer,Juliane Dassler-Plencker,Stefan Holdenrieder,Martin Coenen,Michael Steffens,Marcus Müller,Gunther Hartmann,Julia C. Stingl +10 more
TL;DR: The main finding of this study is that interferon, known to induce depression as adverse drug effect, leads to selective blunting of appetitive rather than affective stimuli.
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