Jordan W. Smoller
Harvard University
580 Papers
2.2K Citations
Jordan W. Smoller is an academic researcher from Harvard University. The author has contributed to research in topics: Medicine & Genome-wide association study. The author has an hindex of 99, co-authored 484 publications. Previous affiliations of Jordan W. Smoller include Rockefeller University & Boston Children's Hospital.
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Papers
Validation of an Electronic Health Record-Based Suicide Risk Prediction Modeling Approach Across Multiple Health Care Systems
Yuval Barak-Corren,Victor M. Castro,Matthew K. Nock,Kenneth D. Mandl,Kenneth D. Mandl,Emily M. Madsen,Ashley N. Seiger,William G. Adams,R Joseph Applegate,Elmer V. Bernstam,Jeffrey G. Klann,Ellen P. McCarthy,Shawn N. Murphy,Marc D. Natter,Brian Ostasiewski,Nandan Patibandla,Gary E. Rosenthal,George Silva,Kun Wei,Griffin M. Weber,Griffin M. Weber,Sarah R. Weiler,Ben Y. Reis,Jordan W. Smoller +23 more
- 02 Mar 2020
TL;DR: Across 5 diverse health care systems, a computationally efficient approach leveraging the full spectrum of structured electronic health record data was able to detect the risk of suicidal behavior in unselected patients and facilitate the development of clinical decision support tools that inform risk reduction interventions.
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•Journal Article
Venlafaxine for panic disorder: results from a double-blind, placebo-controlled study.
Mark H. Pollack,J J Worthington rd,Michael W. Otto,Kristin M. Maki,Jordan W. Smoller,Gisele Gus Manfro,R Rudolph,Jerrold F. Rosenbaum +7 more
TL;DR: Patients treated with venlafaxine experienced significantly greater global improvement than those on placebo and exhibited trends toward greater improvement on anxiety and depression symptoms as assessed by the Hamilton rating scales.
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The genomic psychiatry cohort: Partners in discovery†‡
Michele T. Pato,Janet L. Sobell,Helena Medeiros,Colony Abbott,Brooke M. Sklar,Peter F. Buckley,Evelyn J. Bromet,Michael Escamilla,Ayman H. Fanous,Douglas S. Lehrer,Fabio Macciardi,Dolores Malaspina,Steve McCarroll,Steve McCarroll,Stephen R. Marder,Jennifer L. Moran,Christopher P. Morley,Humberto Nicolini,Diana O. Perkins,Shaun Purcell,Mark Hyman Rapaport,Pamela Sklar,Jordan W. Smoller,James A. Knowles,Carlos N. Pato +24 more
TL;DR: The Genomic Psychiatry Cohort is a longitudinal resource designed to provide the necessary population‐based sample for large‐scale genomic studies, studies focusing on Research Domain Criteria (RDoC) and/or other alternate phenotype constructs, clinical and interventional studies, nested case–control studies, long‐term disease course studies, and genomic variant‐to‐phenotype studies.
GWAS Identifies Risk Locus for Erectile Dysfunction and Implicates Hypothalamic Neurobiology and Diabetes in Etiology
Jonas Bovijn,Leigh Jackson,Jenny C Censin,Chia-Yen Chen,Triin Laisk,Samantha Laber,Teresa Ferreira,Sara L. Pulit,Craig A. Glastonbury,Jordan W. Smoller,Jamie W. Harrison,Katherine S. Ruth,Robin N Beaumont,Samuel E. Jones,Jessica Tyrrell,Andrew R. Wood,Michael N. Weedon,Reedik Mägi,Benjamin M. Neale,Cecilia M. Lindgren,Anna Murray,Michael V. Holmes +21 more
TL;DR: In silico analysis suggests SIM1 to confer ED risk through hypothalamic dysregulation and Mendelian randomization provides evidence that genetic risk of type 2 diabetes mellitus is a cause of ED.
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Placebo analgesia and reward processing: Integrating genetics, personality, and intrinsic brain activity
Rongjun Yu,Randy L. Gollub,Randy L. Gollub,Mark Vangel,Ted J. Kaptchuk,Jordan W. Smoller,Jian Kong,Jian Kong +7 more
TL;DR: The regional homogeneity (ReHo), an index of local neural coherence, in the ventral striatum, was significantly associated with conditioning effects on pain rating changes and the number of Met alleles at the COMT polymorphism was linearly correlated to the suppression of pain.
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