Joonoh Lim
KAIST
3 Papers
Joonoh Lim is an academic researcher from KAIST. The author has contributed to research in topics: Somatic cell & Germline mutation. The author has an hindex of 2, co-authored 3 publications.
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Papers
Clonal dynamics in early human embryogenesis inferred from somatic mutation
Seongyeol Park,Nanda Maya Mali,Ryul Kim,Jeong-Woo Choi,Junehawk Lee,Joonoh Lim,Jung Min Park,Jung Woo Park,Dong Hyun Kim,Taewoo Kim,Kijong Yi,June Hyug Choi,Seong Gyu Kwon,Joo Hee Hong,Jeonghwan Youk,Yohan An,Su Yeon Kim,Soo A Oh,Youngoh Kwon,Dongwan Hong,Moon Kyu Kim,Dong Sun Kim,Ji-Young Park,Ji Won Oh,Ji Won Oh,Young Seok Ju +25 more
TL;DR: In this article, the authors explored whole-genomes of 334 single-cell colonies and targeted deep sequences of 379 bulk tissues obtained from various anatomical locations of seven recently deceased adult human donors.
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Clonal dynamics in early human embryogenesis inferred from somatic mutation
Seongyeol Park,Nanda Maya Mali,Ryul Kim,Jeong-Woo Choi,Junehawk Lee,Joonoh Lim,Jung Min Park,Jung Woo Park,Dong Hyun Kim,Taewoo Kim,Kijong Yi,June Hyug Choi,Seong Gyu Kwon,Joo Hee Hong,Jeonghwan Youk,Yohan An,Su Yeon Kim,Moon Kyu Kim,Dong Sun Kim,Ji-Young Park,Ji Won Oh,Ji Won Oh,Young Seok Ju +22 more
TL;DR: This study explored whole-genomes of 334 single-cell expanded clones and targeted deep-sequences of 379 bulk tissues obtained from various anatomical locations from seven individuals to reconstructed cellular phylogenetic trees that provide novel insights into early human embryogenesis.
Mutational impact and signature of ionizing radiation
Jeonghwan Youk,Hyun Woo Kwon,Hyun Woo Kwon,Joonoh Lim,Eunji Kim,Ryul Kim,Seongyeol Park,Kijong Yi,Sara Jeon,Jinwook Choi,Hyelin Na,Eun-Seok Lee,Young-Won Cho,Dong-Wook Min,Hyo-Jin Kim,Yeong-Rok Kang,Si Ho Choi,Min Ji Bae,Chang Geun Lee,Joon-Goon Kim,Young Seo Kim,Dong Soo Lee,Dong Soo Lee,Tae-You Kim,Tae-You Kim,Taeyun Ku,Su Yeon Kim,Joo-Hyeon Lee,Bon-Kyoung Koo,Hyunsook Lee,On Vox Yi,Eon Chul Han,Ji Hyun Chang,Kyung Su Kim,Tae Gen Son,Young Seok Ju +35 more
TL;DR: In this paper, the authors explored the mutational landscape of normal single-cells after exposure to the various levels of ionizing radiation (IR) and found that 1 Gy of IR exposure generated ∼16 mutational events with a spectrum consisting of predominantly small nucleotide deletions and a few characteristic structural variations.