Joonho Wang
University of California, Los Angeles
5 Papers
124 Citations
Joonho Wang is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Enteroendocrine cell & Receptor. The author has an hindex of 5, co-authored 5 publications.
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Papers
Umami Receptor Activation Increases Duodenal Bicarbonate Secretion via Glucagon-Like Peptide-2 Release in Rats
Joonho Wang,Takuya Inoue,Masaaki Higashiyama,Paul H. Guth,Eli Engel,Jonathan D. Kaunitz,Yasutada Akiba +6 more
TL;DR: Results suggest that luminal l-Glu/IMP-induced DBS is mediated via GLP-2 release and receptor activation followed by VIP and nitric oxide release, which may have additional benefits in glucose metabolism and duodenal mucosal protection and regeneration.
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Dipeptidyl peptidase IV inhibition potentiates amino acid- and bile acid- induced bicarbonate secretion in rat duodenum
Takuya Inoue,Joonho Wang,Masaaki Higashiyama,Sergiy Rudenkyy,Kazuhide Higuchi,Paul H. Guth,Eli Engel,Jonathan D. Kaunitz,Yasutada Akiba +8 more
TL;DR: The modulation of the local concentration of the endogenous secretagogue GLP-2 by luminal compounds and DPPIV inhibition helps regulate protective duodenal HCO3- secretion.
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•Journal Article
Somatostatin Inhibition of Acid and Histamine Release by Activation of Somatostatin Receptor Subtype 2 Receptors in Rats
TL;DR: Results indicate that somatostatin activation of sst2 receptors is the principal physiological pathway for som atostatin-induced inhibition of gastric acid secretion stimulated by either pentagastrin, bethanecol or histamine and of pentagastsrin-stimulated histamine release.
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Endogenous Luminal Surface Adenosine Signaling Regulates Duodenal Bicarbonate Secretion in Rats
Maggie Ham,Misa Mizumori,Chikako Watanabe,Joonho Wang,Takuya Inoue,Takanari Nakano,Paul H. Guth,Eli Engel,Jonathan D. Kaunitz,Yasutada Akiba +9 more
TL;DR: ATP release, ecto-phosphohydrolases, ADA, and concentrative NT may coordinately regulate luminal surface ADO concentration to modulate ADO-P1 receptor signaling in rat duodenum.
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M1719 Umami Receptor Activation Increases Duodenal Bicarbonate Secretion via GLP-2 Release in Rats
TL;DR: Results showed that FOS supplementation increased the expression of GLP1and GPR43-containing enteroendocrine L-cells in the large intestine, suggesting that the prebiotic effects of FOS, such as improvement of the colonic environment to protect against pathogen and inflammation, is associated with theexpression of the SCFA receptor GPR 43.
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