Joo Youn Cho
New Generation University College
274 Papers
1.4K Citations
Joo Youn Cho is an academic researcher from New Generation University College. The author has contributed to research in topics: Medicine & Pharmacokinetics. The author has an hindex of 35, co-authored 230 publications. Previous affiliations of Joo Youn Cho include Seoul National University Hospital & Inje University.
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Papers
Functional characterization of MATE2-K genetic variants and their effects on metformin pharmacokinetics
Jae Yong Chung,Sung Kweon Cho,Tae Hee Kim,Kyoung Hee Kim,Geun Hye Jang,Choon Ok Kim,Eun Mi Park,Joo Youn Cho,In Jin Jang,Ji Ha Choi +9 more
TL;DR: It is suggested that common promoter haplotypes of MATE2-K are associated with the pharmacokinetics of metformin.
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Global metabolomics and targeted steroid profiling reveal that rifampin, a strong human PXR activator, alters endogenous urinary steroid markers.
Bora Kim,Ju Yeon Moon,Man Ho Choi,Hyang Hee Yang,Seung-Hwan Lee,Kyoung Soo Lim,Seo Hyun Yoon,Kyung Sang Yu,In-Jin Jang,Joo Youn Cho +9 more
TL;DR: These human urinary biomarkers may be useful for predicting the extent of PXR activation, monitoring the activity of DMEs, and anticipating drug-drug interactions in patients administered PxR-activating drugs.
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Pharmacokinetics and pharmacodynamics of oral tolvaptan administered in 15- to 60-mg single doses to healthy Korean men.
TL;DR: Tolvaptan showed dose-linear pharmacokinetic characteristics regarding area under the concentration–time curve and resulted in substantial, dose-dependent aquaresis in healthy Korean men.
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Effects of Angelicae tenuissima radix, Angelicae dahuricae radix and Scutellariae radix Extracts on Cytochrome P450 Activities in Healthy Volunteers
Sojeong Yi,Joo Youn Cho,Kyoung Soo Lim,Kyu-Pyo Kim,JaeWoo Kim,Bo-Hyung Kim,Jang Hee Hong,In-Jin Jang,Sang-Goo Shin,Kyung Sang Yu +9 more
TL;DR: Herbal medicines containing S. radix or A. dahuricae radix are candidates for further evaluation of clinically significant CYP-mediated herb-drug interactions in human beings.
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Effect of age on the pharmacokinetics of fimasartan (BR-A-657).
Hae Won Lee,Mi-sun Lim,Sook Jin Seong,Joomi Lee,Jeonghyeon Park,Jeong Ju Seo,Joo Youn Cho,Kyung Sang Yu,Young-Ran Yoon +8 more
TL;DR: While some PK parameters were statistically different between the two groups, the effect of age on the PK was modest (e.g., AUC increase < twofold in older subjects), and fimasartan was well tolerated during this study.
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