Jong Soo Lee
9 Papers
17 Citations
Jong Soo Lee is an academic researcher. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 1, co-authored 1 publications.
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Papers
African Swine Fever Virus EP364R and C129R Target Cyclic GMP-AMP To Inhibit the cGAS-STING Signaling Pathway
Niranjan Dodantenna,Lakmali Ranathunga,W. A. Gayan Chathuranga,Asela Weerawardhana,Ji Won Cha,Ashan Subasinghe,Nuwan Gamage,D. K. Haluwana,Yongkwan Kim,Weon-Hwa Jheong,Haryoung Poo,Jong Soo Lee +11 more
TL;DR: A novel mechanism by which ASFV inhibits IFN-mediated antiviral responses is discovered, and the findings can guide the understanding ofASFV pathogenesis and the development of live attenuated AsFV vaccines.
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Optimal Extraction Conditions of Anti-obesity Lipase Inhibitor from Phellinus linteus and Nutritional Characteristics of the Extracts.
TL;DR: In an effort to develop novel mushroom-derived anti-obesity nutraceuticals, water and ethanol extracts containing the lipaseinhibitory compound from Phellinus linteus were prepared, and their nutritional components were determined.
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Efficacy of a Novel Multiepitope Vaccine Candidate against Foot-and-Mouth Disease Virus Serotype O and A
W. A. Gayan Chathuranga,Chamith Hewawaduge,N. A. Nadeeka Nethmini,Tae-Hwan Kim,Ju Hun Kim,Young-Hoon Ahn,I. J. Yoon,Sung-Sik Yoo,Jonghyun Park,Jong Soo Lee +9 more
TL;DR: In this article , the authors designed two multiepitope recombinant proteins (OVM and AVM) containing antigenic sites (residue of VP1 132-162 and residue of VP 1 192-212) of three topotypes of FMDV serotype O or three topotype of FMM serotype A. Each recombinant protein was efficiently expressed in Escherichia coli with high solubility and the immunogenicity and protective efficacy of the proteins as FMD vaccine candidates were evaluated.
African Swine Fever Virus (ASFV): Immunity and Vaccine Development
Kam Chathuranga,Jong Soo Lee +1 more
TL;DR: The causative agent of the highly contagious disease African swine fever (ASF), which can result in mortality rates of up to 100% in pigs infected by virulent strains as discussed by the authors .
Foot-and-mouth disease virus non-structural protein 2B downregulates the RLR signaling pathway via degradation of RIG-I and MDA5
Asela Weerawardhana,Md. Bashir Uddin,Joo-Hyung Choi,Prabuddha S. Pathinayake,Sung Ho Shin,Kam Chathuranga,Jonghyun Park,Jong Soo Lee +7 more
TL;DR: It is demonstrated that FMDV 2B modulates host IFN signal pathway by the degradation of RIG-I and MDA5, and it is identified that the C-terminal amino acids 126-154 of FMDv 2B are essential for 2B-mediated degradation of the RIG/MDA5.