Jonathan Pansieri
University of Grenoble
15 Papers
57 Citations
Jonathan Pansieri is an academic researcher from University of Grenoble. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 6, co-authored 6 publications. Previous affiliations of Jonathan Pansieri include Umeå University.
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Papers
Ultraviolet–visible–near-infrared optical properties of amyloid fibrils shed light on amyloidogenesis
Jonathan Pansieri,Jonathan Pansieri,Véronique Josserand,Sun-Jae Lee,Anaëlle Rongier,Daniel Imbert,M. Sallanon,M. Sallanon,Eniko Veronika Kovari,Thomas G. Dane,Charlotte Vendrely,Charlotte Vendrely,Odette Chaix-Pluchery,Mélanie Guidetti,Julien Vollaire,Arnold Fertin,Yves Usson,Patrice Rannou,Jean-Luc Coll,C. Marquette,Vincent Forge +20 more
TL;DR: Two optical signatures of amyloid fibres—luminescence in the blue and a near-infrared signal, which can be observed in in vitro and in vivo tissues—are reported and could open the door to innovative diagnostic strategies for neurodegenerative diseases.
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Gd-nanoparticles functionalization with specific peptides for ß-amyloid plaques targeting
Marie Plissonneau,Jonathan Pansieri,Laurence Heinrich-Balard,Laurence Heinrich-Balard,Jean-François Morfin,Nathalie Martine Stransky-Heilkron,Pascaline Rivory,Pascaline Rivory,Pierre Mowat,Mireille Dumoulin,Richard Cohen,Richard Cohen,Eric Allémann,Éva Tόth,Maria João Saraiva,Cédric Louis,Olivier Tillement,Vincent Forge,François Lux,C. Marquette +19 more
TL;DR: In this paper, the authors have functionalized gadolinium-based MRI nanoparticles with peptides highly specific for Aβ amyloid fibrils, LPFFD and KLVFF.
Multimodal imaging Gd-nanoparticles functionalized with Pittsburgh compound B or a nanobody for amyloid plaques targeting
Jonathan Pansieri,Marie Plissonneau,Nathalie Martine Stransky-Heilkron,Mireille Dumoulin,Laurence Heinrich-Balard,Pascaline Rivory,Jean-François Morfin,Éva Tóth,Maria João Saraiva,Eric Allémann,Olivier Tillement,Vincent Forge,François Lux,C. Marquette +13 more
TL;DR: Nanoparticles functionalized with either the Pittsburgh compound B or a nanobody (B10AP) could represent promising flexible and multimodal imaging tools for the early diagnostic of amyloid diseases, in other words, Alzheimer's disease, Type 2 diabetes mellitus and the familial amyloidsotic polyneuropathy.
Gd-nanoparticles functionalization with specific peptides for ß -amyloid plaques
Jonathan Pansieri,Laurence Heinrich‑Balard,Nathalie Stransky‑Heilkron,Pascaline Rivory,Pierre Mowat,Mireille Dumoulin,Richard Cohen,Eric Allémann,Maria João Saraiva,Cédric Louis,Olivier Tillement,Vincent Forge,François Lux,C. Marquette +13 more
- 01 Jan 2016
TL;DR: In this article, a functionalized gadolinium-based MRI nanoparticles (AGuIX) with peptides highly specific for Aβ amyloid fibrils, LPFFD and KLVFF, was tested with Aβ(1−42)-fibrils and with mutated (V30M) transthyretin (TTR), with equilibrium dissociation constant (K d) values of 403 and 350 µM respectively.
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Mass and charge distributions of amyloid fibers involved in neurodegenerative diseases: mapping heterogeneity and polymorphism
Jonathan Pansieri,Mohammad A. Halim,Charlotte Vendrely,Mireille Dumoulin,François Legrand,François Legrand,M. Sallanon,Sabine Chierici,Simona Denti,Xavier Dagany,Philippe Dugourd,C. Marquette,Rodolphe Antoine,Vincent Forge +13 more
TL;DR: Characterization by charge detection mass spectrometry of amyloid fibers involved in neurodegenerative diseases: Aβ peptide, tau and α-synuclein.