Jonathan Lee
University of Pennsylvania
27 Papers
9 Citations
Jonathan Lee is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Medicine & Heart failure. The author has an hindex of 10, co-authored 17 publications. Previous affiliations of Jonathan Lee include Stanford University & Hospital of the University of Pennsylvania.
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Papers
TDP-43 Is Intrinsically Aggregation-prone, and Amyotrophic Lateral Sclerosis-linked Mutations Accelerate Aggregation and Increase Toxicity
Brian S. Johnson,David Snead,Jonathan Lee,J. Michael McCaffery,James Shorter,Aaron D. Gitler +5 more
TL;DR: It is reported that, in the absence of other components, TDP-43 spontaneously forms aggregates bearing remarkable ultrastructural similarities to TDP -43 deposits in degenerating neurons of ALS FTLD-U patients.
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Left Atrial Phasic Function by Cardiac Magnetic Resonance Feature Tracking Is a Strong Predictor of Incident Cardiovascular Events.
Julio A. Chirinos,Julio A. Chirinos,Julio A. Chirinos,Mayank Sardana,Bilal Ansari,Vaibhav Satija,Daniel Kuriakose,Ilaina Edelstein,Garrett Oldland,Garrett Oldland,Garrett Oldland,Rachana Miller,Rachana Miller,Rachana Miller,Swetha Gaddam,Swetha Gaddam,Jonathan Lee,Arpita Suri,Scott Akers +18 more
TL;DR: Phasic LA function measured using feature-tracking magnetic resonance imaging feature tracking is independently predictive of the risk of incident HF admission or death, even after adjusting for LA volume and left ventricular remodeling.
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Cx29 and Cx32, two connexins expressed by myelinating glia, do not interact and are functionally distinct.
Meejin Ahn,Jonathan Lee,Andreas Gustafsson,Alan D. Enriquez,Eric Lancaster,Jai Yoon Sul,Philip G. Haydon,David L. Paul,Yan Huang,Charles K. Abrams,Steven S. Scherer +10 more
TL;DR: It is shown that, in contrast to Cx32, Cx29 does not form gap junction plaques or functional gap junctions in transfected cells, and homomeric interactions of Cx 29 and especially Cx 32 largely require other domains: the N‐terminus, transmembrane domains, and extracellular loops.
Right Atrial Phasic Function in Heart Failure With Preserved and Reduced Ejection Fraction
Snigdha Jain,Daniel Kuriakose,Ilaina Edelstein,Bilal Ansari,Garrett Oldland,Swetha Gaddam,Khuzaima Javaid,Pritika Manaktala,Jonathan Lee,Rachana Miller,Scott Akers,Julio A. Chirinos,Julio A. Chirinos +12 more
TL;DR: Phasic RA function is predictive of the risk of all-cause death in a diverse group of subjects with and without heart failure, and RA conduit and reservoir function are independent predictors of mortality.
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Serum Albumin Is a Marker of Myocardial Fibrosis, Adverse Pulsatile Aortic Hemodynamics, and Prognosis in Heart Failure With Preserved Ejection Fraction
Stuart B. Prenner,Stuart B. Prenner,Raj Pillutla,Sowjanya Yenigalla,Sowmya Gaddam,Jonathan Lee,Jonathan Lee,Mary Jo Obeid,Armghan H Ans,Qasim Jehangir,Jessica Kim,Jessica Kim,Payman Zamani,Jeremy A. Mazurek,Scott Akers,Julio A. Chirinos,Julio A. Chirinos +16 more
TL;DR: Serum albumin is associated with myocardial fibrosis, adverse pulsatile aortic hemodynamics, and prognosis in HFpEF and is a strong predictor of death or heart failure hospitalization even after adjustment for N‐terminal pro B‐type natriuretic peptide levels and the MAGGIC risk score.
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