Jonathan Hoyne
University of South Florida
10 Papers
32 Citations
Jonathan Hoyne is an academic researcher from University of South Florida. The author has contributed to research in topics: Apolipoprotein E & Biology. The author has an hindex of 6, co-authored 6 publications.
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Papers
No association between the intronic presenilin-1 polymorphism and Alzheimer's disease in clinic and population-based samples
Xingang Cai,Judith Stanton,Dani Fallin,Jonathan Hoyne,Ranjan Duara,Michael Gold,Steve Sevush,Paul Scibelli,Fiona Crawford,Michael Mullan +9 more
TL;DR: The results are consistent with those of other researchers and do not support the conclusion that the PS1 polymorphism is associated with late-onset AD.
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Familial and population-based studies of apolipoprotein E and Alzheimer's disease.
Michael Mullan,Paul Scibelli,Ranjan Duara,Danielle Fallin,Michael Gold,John A. Schinka,Jonathan Hoyne,Aaron Osborne,Steven Sevush,Fiona Crawford +9 more
TL;DR: It is concluded that any selection procedure tending to enrich samples for positive family history will also tend to artificially increase APOE epsilon 4 allele frequencies in probands, which is of significance in samples drawn from clinical settings where referral may be influenced by previous known family history.
26
No interaction between the APOE and the alpha-1-antichymotrypsin genes on risk for Alzheimer's disease
Danielle Fallin,Sarah A. J. Reading,John A. Schinka,Jonathan Hoyne,Paul Scibelli,Michael Gold,Fiona Crawford,Michael Mullan +7 more
TL;DR: By this analysis, ACT genotyping does not provide additional information about an individual's risk of Alzheimer's disease beyond the risk information conferred by APOE genotype alone, and Logistic regression analysis excludes ACT or the interaction between ACT and APOE as significant contributors in the prediction of disease status.
20
Occurrence of the Cys311 DRD2 variant in a pedigree multiply affected with panic disorder
Fiona Crawford,Jonathan Hoyne,Patricia Diaz,Aaron Osborne,Jocelyn Dorotheo,David V. Sheehan,Michael Mullan +6 more
TL;DR: The data suggests that the rare DRD2 codon 311 variant (Ser-->Cys) has no pathogenic role in panic disorder.
14
Journal Pre-proof Neurofilament light chain and vaccination status associate with clinical outcomes in severe COVID-19
Young Erben,Mercedes Prudencio,C. Marquez,Karen Jansen-West,Michael G. Heckman,Launia J. White,Judith Dunmore,Casey Cook,Meredith,Thomas M. Lilley,Neda Qosja,Yuping Song,Rana Hanna Al Shaikh,Lillian M. Daughrity,Jordan L. Bartfield,Gregory S. Day,Bjorn Oskarsson,Katharine Nicholson,Zbigniew K. Wszolek,Jonathan Hoyne,Tania F. Gendron,James F. Meschia,Leonard Petrucelli +22 more
TL;DR: The findings support the utility of measuring NFL shortly after hospital admission to estimate disease severity and show that race does not influence clinical outcomes caused by COVID-19 assuming equivalent access to care, and that vaccination may lessen the degree of CO VID-19-caused disability.