Jon Brynildsen
Akershus University Hospital
23 Papers
68 Citations
Jon Brynildsen is an academic researcher from Akershus University Hospital. The author has contributed to research in topics: Heart failure & Medicine. The author has an hindex of 6, co-authored 17 publications.
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Papers
Severity of obstructive sleep apnea is associated with cardiac troponin I concentrations in a community-based sample: data from the Akershus Sleep Apnea Project.
Gunnar Einvik,Helge Røsjø,Anna Randby,Silje K. Namtvedt,Harald Hrubos-Strøm,Jon Brynildsen,Virend K. Somers,Torbjørn Omland +7 more
TL;DR: Increased obstructive sleep apnea severity is independently associated with higher concentrations of hs-TnI, suggesting that frequent apneas or hypoxemia in OSA may cause low-grade myocardial injury.
Influence of Glycosylation on Diagnostic and Prognostic Accuracy of N-Terminal Pro–B-Type Natriuretic Peptide in Acute Dyspnea: Data from the Akershus Cardiac Examination 2 Study
Helge Røsjø,Mai Britt Dahl,Marit Jørgensen,Ragnhild Røysland,Jon Brynildsen,Alessandro Cataliotti,Geir Christensen,Arne Didrik Høiseth,Tor-Arne Hagve,Torbjørn Omland +9 more
TL;DR: NT-proBNP concentrations were higher, and diagnostic and prognostic accuracy was improved, by pretreating tubes with deglycosylation enzymes, as assessed by the net reclassification index.
Glycosylated Chromogranin A in Heart Failure: Implications for Processing and Cardiomyocyte Calcium Homeostasis.
Anett Hellebø Ottesen,Cathrine R. Carlson,William E. Louch,Mai Britt Dahl,Ragnhild Askeland Sandbu,Rune F. Johansen,Hilde Jarstadmarken,Magnar Bjørås,Arne Didrik Høiseth,Jon Brynildsen,Ivar Sjaastad,Mats Stridsberg,Torbjørn Omland,Geir Christensen,Helge Røsjø +14 more
TL;DR: CgA-to-CST conversion in HF is impaired because of hyperglycosylation, which is associated with clinical outcomes in acute HF, and the mechanism for increased mortality may be dysregulated cardiomyocyte Ca2+ handling because of reduced CaMKIIδ inhibition.
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Diagnostic Thresholds for Pre–Diabetes Mellitus and Diabetes Mellitus and Subclinical Cardiac Disease in the General Population: Data From the ACE 1950 Study
Peder L. Myhre,Magnus Nakrem Lyngbakken,Trygve Berge,Ragnhild Røysland,Erika N. Aagaard,Osman Pervez,Brede Kvisvik,Jon Brynildsen,Jon Norseth,Arnljot Tveit,Kjetil Steine,Torbjørn Omland,Helge Røsjø +12 more
TL;DR: In this paper, the association between glycated hemoglobin A1c (HbA1c) and subclinical cardiac disease was found to be associated with left ventricular remodeling and incident heart failure.
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The influence of heart failure co-morbidity on high-sensitivity troponin T levels in COPD exacerbation in a prospective cohort study: data from the Akershus cardiac examination (ACE) 2 study
Arne Didrik Høiseth,Jon Brynildsen,Tor-Arne Hagve,Geir Christensen,Vidar Søyseth,Omland Torbjørn,Helge Røsjø +6 more
TL;DR: hs-TnT levels are influenced by myocardial dysfunction/HF in AECOPD, but provide independent prognostic information, and the prognostic merit of hs-TNT cannot be attributed to HF alone.
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