5 Papers
2 Citations
John Walker is an academic researcher from Uniformed Services University of the Health Sciences. The author has contributed to research in topics: Traumatic brain injury & Poison control. The author has an hindex of 4, co-authored 5 publications.
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Papers
Time-Dependent Changes in Serum Level of Protein Biomarkers after Focal Traumatic Brain Injury
Elham Rostami,Andrea Gyorgy,Johan Davidsson,John Walker,Daniel Wingo,Maria Angeria,Bo-Michael Bellander,Denes V. Agoston,Mårten Risling +8 more
TL;DR: The study suggests that pen-TBI results in both acute axonal and neuronal damages as well as delayed changes likely part of the ongoing secondary injury process, and underline the importance of monitoring changes in serum biomarker levels for more accurate assessment of injury severity and outcome.
Proteomic-based identification of injury-specific patterns of biomarkers in rotational and penetrating TBI
Elham Rostami,Andrea Gyorgy,Johan Davidsson,John Walker,Daniel Wingo,Maria Angeria,Bo Mikael Bellander,Denes V. Agoston,Mårten Risling +8 more
- 01 Jan 2010
TL;DR: These are the first results showing TBI – type specific changes in different proteins that can be considered as future biomarkers.
2
Stress and Traumatic Brain Injury: A Behavioral, Proteomics, and Histological Study
Sook-Kyung C. Kwon,Erzsebet Kovesdi,Andrea Gyorgy,Daniel Wingo,Alaa Kamnaksh,John Walker,Joseph B. Long,Denes V. Agoston +7 more
TL;DR: It is suggested that exposure to repeated stress alone causes a transient increase in anxiety and no significant memory impairment or cellular and molecular changes, and repeated stress and blast results in lasting behavioral, molecular, and cellular abnormalities characterized by memory impairment, neuronal and glial cell loss, inflammation, and gliosis.
Reverse phase protein microarray technology in traumatic brain injury.
Andrea Gyorgy,John Walker,Daniel Wingo,Ofer Eidelman,Harvey B. Pollard,Andras Molnar,Denes V. Agoston +6 more
TL;DR: This work believes that using stringent quality controls, improved bioinformatics analysis and interpretation of primary RPPA data, this method will significantly contribute in generating new level of understanding about complex disorders at the level of systems biology.
Time-dependent changes in serum biomarker levels after blast traumatic brain injury
Andrea Gyorgy,Geoffrey S.F. Ling,Daniel Wingo,John Walker,Lawrence C. Tong,Steven Parks,Adolph Januszkiewicz,Richard Baumann,Denes V. Agoston +8 more
TL;DR: It is concluded that the sudden increase in serum NF-H levels following bTBI may be a useful indicator of injury severity, and if additional studies verify the findings, can be developed into a useful diagnostic tool for predicting the extent of damage following b TBI.