John W. Mellors

TL;DR: The authors compared and contrasted key elements of the AIDS and COVID-19 misinfodemics, to identify common features, and, based on experience with the AIDS pandemic, recommend actions to control and reverse the SARS-CoV-2 mis-infodemic that contributed to erode the trust between the public and scientists and governments and has created barriers to control of COVID19.

TL;DR: A questionnaire to develop a questionnaire that measures attitudes and concerns about HIV treatment trials among HIV-infected African Americans at a university-based clinic found neither trust/distrust in the medical profession nor beliefs about the dishonesty of researchers was associated with research participation rates or willingness to participate in future HIV treatment Trials.

TL;DR: The appearance of genetically uniform virus populations and the lack of divergence after prolonged cART and cART interruption provide strong evidence that HIV-1 persists in long-lived cells infected before cART was initiated, that some of these infected cells may be capable of proliferation, and that on-going cycles of viral replication are not evident.

TL;DR: In individuals on suppressive ART with incomplete CD4+ T-cell recovery, maraviroc intensification did not affect measures of HIV-1 persistence but did decrease persistent CD4-T-cell immune activation especially in individuals with low preintensification levels of HIV -1 DNA.