John S. Haurum
Aarhus University
6 Papers
231 Citations
John S. Haurum is an academic researcher from Aarhus University. The author has contributed to research in topics: Collectin & CTL*. The author has an hindex of 6, co-authored 6 publications.
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Papers
Complement activation upon binding of mannan-binding protein to HIV envelope glycoproteins.
TL;DR: Complement activation by HIV envelope glycoproteins was found to be mediated by the binding of MBP to carbohydrates on natural envelope protein produced in virus-infected cells, as well as on glycosylated recombinant envelope proteins produced in insect cells.
153
Interaction of C1q receptor with lung surfactant protein A.
TL;DR: The results indicate that interaction of SP‐A with U937 cells triggers the expression of an intracellular pool of C1qR, which is specific, saturable, salt dependent and is inhibited by purified C 1qR and byC1q.
139
Studies on the carbohydrate-binding characteristics of human pulmonary surfactant-associated protein A and comparison with two other collectins: mannan-binding protein and conglutinin.
TL;DR: It seems likely that SP-A, like MBP and conglutinin, may mediate anti-microbial activity through binding to carbohydrates on the microorganisms and collectin receptors on phagocytic cells.
MUC1 peptide epitopes associated with five different H‐2 class I molecules
TL;DR: The induction of murine CD8+ major histocompatibility complex (MHC) class I‐restricted cytotoxic T cells (CTL) recognizing the 20‐amino acid repeat region of the human mucin 1 (MUC1) variable number of tandem repeats region (VNTR) is described.
74
Pollen grains bind to lung alveolar type II cells (A549) via lung surfactant protein A (SP-A)
TL;DR: The binding of SP-A to pollen grains and their aqueous extracts was calcium ion dependent and was inhibited by mannose, and is therefore mediated by the lectin domain, which suggests that pollen grains or other carbohydrate-bearing particles could potentially interact with different cell types via the collectin receptor (C1q Receptor) in the presence ofSP-A.