John Ostuni
National Institutes of Health
22 Papers
396 Citations
John Ostuni is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Grey matter & Lesion. The author has an hindex of 17, co-authored 22 publications. Previous affiliations of John Ostuni include Armed Forces Institute of Pathology.
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Papers
Evidence of Left Inferior Frontal–Premotor Structural and Functional Connectivity Deficits in Adults Who Stutter
Soo Eun Chang,Barry Horwitz,John Ostuni,Richard C. Reynolds,Christy L. Ludlow,Christy L. Ludlow +5 more
TL;DR: The authors' data provide strongest support for deficient left hemisphere inferior frontal to premotor connectivity as a neural correlate of stuttering.
Interferon beta-1b and intravenous methylprednisolone promote lesion recovery in multiple sclerosis.
TL;DR: IFNβ-1b and IVMP reduce tissue damage and promote lesion recovery in RRMS patients and may be related to its inhibitory effect on demyelination.
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Thalamic Involvement and Its Impact on Clinical Disability in Patients with Multiple Sclerosis: A Diffusion Tensor Imaging Study at 3T
Fernanda Tovar-Moll,Iordanis E. Evangelou,Annie W. Chiu,Nancy Richert,John Ostuni,Joan Ohayon,Sungyoung Auh,Mary Ehrmantraut,S. L. Talagala,Henry F. McFarland,Francesca Bagnato +10 more
TL;DR: The assessment of the integrity of the thalamus with DTI is a promising metric as a marker of disease for future studies and the strength of association between thalamic DTI measures and functional impairment was in the same range as those seen with standard MR imaging disease measures.
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Study of relapsing remitting experimental allergic encephalomyelitis SJL mouse model using MION-46L enhanced in vivo MRI: early histopathological correlation.
Su Xu,E. Kay Jordan,Stefan Brocke,Jeff W.M. Bulte,Laura Quigley,Nancy Tresser,John Ostuni,Yihong Yang,Henry F. McFarland,Joseph A. Frank +9 more
TL;DR: MION‐46L enhanced MRI may be used to provide a unique sensitivity in EAE lesion detection and correlate imaging to histopathology, and eventually assist in preclinical screening of new experimental therapies directed at patients with multiple sclerosis (MS).
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•Journal Article
Serial whole-brain magnetization transfer imaging in patients with relapsing-remitting multiple sclerosis at baseline and during treatment with interferon beta-1b
TL;DR: Occult disease in normal-appearing white matter of patients with relapsing-remitting MS measured by MTR parallels the waxing and waning pattern of enhancing lesions and bulk white matter lesion load during the baseline period.
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