John Mac Sharry
National University of Ireland
6 Papers
3 Citations
John Mac Sharry is an academic researcher from National University of Ireland. The author has contributed to research in topics: Interleukin 5 & Myenteric plexus. The author has an hindex of 2, co-authored 5 publications.
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Papers
Bifidobacterium infantis 35624 protects against salmonella-induced reductions in digestive enzyme activity in mice by attenuation of the host inflammatory response.
Erin L. Symonds,Caitlin O'Mahony,Susan Lapthorne,David O'Mahony,John Mac Sharry,Liam O'Mahony,Liam O'Mahony,Fergus Shanahan +7 more
TL;DR: Salmonella infection reduces the small intestinal brush border enzyme activity in mice, with the level of reduction and associated weight loss increasing with dose and duration of infection.
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Concomitant Exposure to Ovalbumin and Endotoxin Augments Airway Inflammation but Not Airway Hyperresponsiveness in a Murine Model of Asthma
John Mac Sharry,Karim H. Shalaby,Cinzia L. Marchica,Soroor Farahnak,Tien Chieh-Li,Susan Lapthorne,Salman T. Qureshi,Fergus Shanahan,James G. Martin +8 more
TL;DR: Contaminating LPS is not required for induction of airway hyperresponsiveness but amplifies the Th2 inflammatory response and is a critical mediator of the neutrophil, Th1 and T regulatory cell responses to OVA.
MiR-146a Negatively Regulates IL-17A Inflammatory Response and is Elevated in Intestinal Epithelial Cells From Inflammatory Bowel Disease (IBD) Patients
Monica Ambrose,Annette O'Keeffe,Aine Fanning,Carola T. Murphy,Grainne Hurley,Aoife Quinlan,John Mac Sharry,Marie-Louise Hammarström,Edith M. Hessel,Kevin A.W. Lee,Fergus Shanahan,Silvia Melgar,Kenneth Nally +12 more
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Su2001 Altered Expression and Activation of the CXCR3/CXCL10 Chemokine System in Irritable Bowel Syndrome (IBS) Mucosal Biopsy Tissue
Gerard M. Moloney,Aine Fanning,John Mac Sharry,Lindsay J. Hall,Fergus Shanahan,Eamonn Martin Quigley,Silvia Melgar,Kenneth Nally +7 more
TL;DR: Reduced small bowel transit 12h following TNBS suggests rapid functional changes in response to the inflammatory insult, and supports the concept that PVG neurons contribute to small bowel motor dysfunction during colitis.
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