Resume La nosologie des demences acquises de l’adulte a considerablement evolue lors des dernieres annees. Les connaissances physiopathologiques se sont etendues, permettant de decrire de nouveaux cadres nosologiques. Le clinicien doit apprendre a rechercher ces nouvelles entites, a cote des formes mieux connues comme la maladie d’Alzheimer. Dans cette approche, il doit reconnaitre les traits semiologiques saillants de ces entites et apprendre a utiliser d’autres marqueurs soit biologiques (comme les marqueurs du LCR), soit en imagerie cerebrale (IRM ou imagerie metabolique). Cet article presente une revue des concepts nosologiques actuels.

Classification des démences : aspects nosologiques

In this issue of Neurology , Gorno-Tempini et al.1 and Rosen et al.2 present studies characterizing neuroimaging and behavioral changes in subtypes of primary progressive aphasia (PPA). They add new information to a large and growing body of literature on the frontotemporal lobar degenerations (FTLD), the second most common cause of dementia in persons under age 65. As this group of illnesses is still less common than other causes of dementia, such as Alzheimer disease (AD) and vascular dementia, both studies were made possible through the systematic study of a large number of such patients performed at a tertiary referral center.

In order to explore the anatomic basis for mutism in progressive nonfluent aphasia (PNFA), one form of FTLD, Gorno-Tempini et al.1 compared gray matter volumes in regions of interest between mute and non-mute patients with PNFA using voxel-based morphometry. Many patients with PNFA eventually develop mutism so it is important to note that patients and controls in this study were matched for disease duration. These investigators found more severe atrophy in the left anterior insula and inferior frontal lobe in persons with PNFA with more prominent atrophy in the pars opercularis and underlying basal ganglia in …

Visualizing language deterioration in progressive aphasias

Handle everyday research tasks with reliable, citation-backed results

Your personal Research Agent to handle research tasks with citation-backed results

Popular Tasks used by Researchers

How can I help with your research?

Meet SciSpace

Get more enhanced response by uploading the PDFs you want me to reference.

No relevant PDFs in your library

SciSpace is the AI research assistant for academics. Run systematic literature reviews on 280M+ papers, and write papers with cited sources. Trusted by 1M+ students, PhDs & researchers.

SciSpace | AI for Research

Analyze PDFs

Code & Manuscripts

Funding & Grants

Literature & Patents

Medical & Clinical Data

Systematic Review

Visualize & Present

Web & Data

Build a Google Scholar-like website for your research.

Build a website

Create charts and images for your research

Create a Chart

Write a paper for submission to a journal

Draft a manuscript

Patent Search

Design eye-catching scientific posters in minutes.

Scientific Poster Generation

Systematic Literature Review

One task is running at the moment. Your messages will be shown right after.

Drag and drop or click here to browse

Loved by <highlight>1 million+</highlight> researchers

Extract a list of specific topics and their sources from unstructured text

Topics

Compare and analyze relevant papers that matches with your search

Papers

Get insights from PDFs and bookmarked papers from your library

My library

Recent searches

Try searching for:

Catch AI-generated content in scholarly and non-scholarly content

{ai} Detector

Ai Writer

Get PDF Summaries, highlighted text explanations 

Chat with PDF

Effortlessly create in-text citations and bibliographies in APA and 2,500 other formats

Citation generator

Get explanations, summaries, and answers on academic papers

Ease up your research workflow with {scispace}'s cohort of exciting AI tools

Elevate your academic writing skills and convey your ideas the way you want

Paraphraser

Explore our range of reading and writing tools

Your file is being prepared and should be ready in a few minutes. If it's a large file, it might take a bit longer. You can close this window, and we'll email you the file when it's done.

You have reached a maximum limit of <strong>{limit}</strong> columns in the table. Remove at least <strong>1</strong> column to add or create another one.

John M. Ringman

Author Tools

Chat about Author

Papers

Visualizing language deterioration in progressive aphasias