John M. Northover
Cancer Research UK
6 Papers
31 Citations
John M. Northover is an academic researcher from Cancer Research UK. The author has contributed to research in topics: HPV infection & Anal dysplasia. The author has an hindex of 6, co-authored 6 publications.
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Papers
Anal cancer in renal transplant patients
TL;DR: A comprehensive literature review was performed to examine the prevalence of anal cancer, anal intraepithelial neoplasia (AIN) and anal human papillomavirus (HPV) infection in renal transplant recipients who are at risk of cancer due to iatrogenic immunosuppression as mentioned in this paper.
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The influence of circumferential resection margins on long-term outcomes following rectal cancer surgery.
TL;DR: Circumferential margins ≤2 mm are associated with significantly reduced cancer-specific survival, and margins ≥1 mm with increased local recurrence, when other factors are accounted for, challenging the assumption that a circumferential resection margin of ≤1 mm is safe.
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Human papillomavirus infection and anal dysplasia in renal transplant recipients
TL;DR: The demographics of anal HPV and associated risk factors were investigated in the renal transplant population, and additional risk factors for HPV‐related disease have not been studied in this population.
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Assessment of microvessel density and carbonic anhydrase-9 (CA-9) expression in rectal cancer.
Shahnawaz Rasheed,Adrian L. Harris,Paris P. Tekkis,Helen Turley,Andrew Silver,P J McDonald,Ian C. Talbot,Rob Glynne-Jones,John M. Northover,Thomas Guenther +9 more
TL;DR: MVD was higher in more advanced T- and N-stages and may be used as a determinant of survival in patients with rectal adenocarcinomas, and CA-9 expression was seen more often in earlier Dukes' stages, possibly representing an early tumor hypoxic response.
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Angiogenesis and hypoxic factors in colorectal cancer.
TL;DR: It is postulated that, with a greater understanding of the angiogenic mechanisms that govern tumor growth, anti-angiogenic compounds may be introduced to combine with conventional means to combat the growth and spread of malignant disease.
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