John M. Hudson
Sunnybrook Health Sciences Centre
35 Papers
141 Citations
John M. Hudson is an academic researcher from Sunnybrook Health Sciences Centre. The author has contributed to research in topics: Medicine & Sunitinib. The author has an hindex of 15, co-authored 32 publications. Previous affiliations of John M. Hudson include University of Toronto & Sunnybrook Research Institute.
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Papers
Dynamic Microbubble Contrast-enhanced US to Measure Tumor Response to Targeted Therapy: A Proposed Clinical Protocol with Results from Renal Cell Carcinoma Patients Receiving Antiangiogenic Therapy
Ross Williams,John M. Hudson,B. Lloyd,Ahthavan R. Sureshkumar,Gordon Lueck,Laurent Milot,Mostafa Atri,Georg A. Bjarnason,Peter N. Burns +8 more
TL;DR: DCE US provides reproducible and sensitive assessment of vascular changes in response to antiangiogenic therapy and could not be used to predict long-term assessment of best response by using RECIST.
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Inter- and Intra-Operator Reliability and Repeatability of Shear Wave Elastography in the Liver: A Study in Healthy Volunteers
TL;DR: This study assessed the reproducibility of shear wave elastography in the liver of healthy volunteers and found that intra- and inter-operator reliability and repeatability were quantified in three different liver segments in a sample of 15 subjects.
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Imaging innovations for cancer therapy response monitoring
Ali Sadeghi-Naini,Omar Falou,John M. Hudson,Colleen Bailey,Peter N. Burns,Martin J. Yaffe,Greg J. Stanisz,Michael C. Kolios,Gregory J. Czarnota +8 more
TL;DR: Considerable developments introduced to improve the precision of treatment response monitoring are expected in the near future to provide clinical approaches to personalized therapy in which therapies can be adapted based on the detection of functional physiology-based responses.
Reprint of: Outcomes in patients with metastatic renal cell cancer treated with individualized sunitinib therapy: Correlation with dynamic microbubble ultrasound data and review of the literature
Georg A. Bjarnason,Bishoy Khalil,John M. Hudson,Ross Williams,Laurent Milot,Mostafa Atri,Alex Kiss,Peter N. Burns +7 more
TL;DR: Individualized sunitinib scheduling based on toxicity may improve PFS and OS, and this hypothesis is supported by several other respective data that are reviewed.
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Improved Flow Measurement Using Microbubble Contrast Agents and Disruption-Replenishment: Clinical Application to Tumour Monitoring
John M. Hudson,John M. Hudson,Ross Williams,Ross Williams,Brendan Lloyd,Brendan Lloyd,Mostafa Atri,Tae Kyoung Kim,Georg A. Bjarnason,Peter N. Burns,Peter N. Burns +10 more
TL;DR: To further decrease flow measurement variability, this work examines a method that exploits microbubble flow dynamics to discard the contribution of flow in large arteries and isolate the portion of the tumour microvasculature that is most sensitive to vessel targeting therapies.
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