John Jackson
Trinity College, Dublin
15 Papers
248 Citations
John Jackson is an academic researcher from Trinity College, Dublin. The author has contributed to research in topics: Coeliac disease & Autoantibody. The author has an hindex of 11, co-authored 15 publications.
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Papers
Distinct and overlapping effector functions of expanded human CD4+, CD8α+ and CD4-CD8α- invariant natural killer T cells.
Vincent P. O’Reilly,Shijuan G. Zeng,Gabriel Bricard,Ann Atzberger,Andrew E. Hogan,John Jackson,Conleth Feighery,Steven A. Porcelli,Derek G. Doherty +8 more
TL;DR: Use of enriched CD8α+, DN or CD4+ iNKT cells may optimally harness the immunoregulatory properties of iN KT cells for treatment of disease.
Dimensions of occupational mobility in the Republic of Ireland
Michael Hout,John Jackson +1 more
TL;DR: In this paper, the authors present data on occupational mobility in the Republic of Ireland in greater detail than has been available previously, and find that the relative low mobility rate in Ireland is due to the combined effects of an occupational composition that favours immobility and a pattern of strong association between class origins and destinations.
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T cell proliferation, MHC class II restriction and cytokine products of gliadin-stimulated peripheral blood mononuclear cells (PBMC).
TL;DR: The results suggest, as manifest by IFN‐γ production, that gliadin stimulates a Th1/Th0‐ like response in coeliac patients and a Th0‐like response in healthy controls.
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Circulating levels of β2-glycoprotein I in thrombotic disorders and in inflammation
F Lin,R Murphy,B White,Jacinta Kelly,Conleth Feighery,R Doyle,S J Pittock,J Moroney,Owen P. Smith,Wendy Livingstone,C. Keenan,John Jackson +11 more
TL;DR: Low levels of β2GPI are found in healthy individuals and in elderly patients with myocardial syndrome, suggesting that the reduced levels were not a transient post-event phenomenon and in patients with inflammation, which showed a significant negative correlation with CRP.
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Flow cytometric measurement of intracellular migration inhibition factor and tumour necrosis factor alpha in the mucosa of patients with coeliac disease.
J. O'Keeffe,Sara Lynch,Alex Whelan,John Jackson,Nicholas P. Kennedy,D. G. Weir,Conleth Feighery +6 more
TL;DR: Investigation of the expression of two proinflammatory cytokines, migration inhibition factor (MIF) and tumour necrosis factor alpha (TNF‐α) in duodenal biopsy specimens from patients with coeliac disease on a gluten‐free diet and normal control subjects shows up‐regulated expression of MIF and TNF‐ α in IELs and epithelial cells of histologically normal mucosa in patients with Coeliac Disease.
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