John F. Allen
Coventry University
406 Papers
3.8K Citations
John F. Allen is an academic researcher from Coventry University. The author has contributed to research in topics: Photosystem & Medicine. The author has an hindex of 79, co-authored 401 publications. Previous affiliations of John F. Allen include Centre for Life & University of California, Berkeley.
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Papers
Chlorophyll Biosynthesis Gene Evolution Indicates Photosystem Gene Duplication, Not Photosystem Merger, at the Origin of Oxygenic Photosynthesis
Filipa L. Sousa,Liat Shavit-Grievink,Liat Shavit-Grievink,John F. Allen,John F. Allen,William Martin +5 more
TL;DR: It is inferred that the cell that first synthesized chlorophyll was a cobalamin-dependent, heme-synthesizing, diazotrophic anaerobe, thereby excluding models of fusion at the origin of cyanobacteria and supporting the selective-loss hypothesis.
A clinical study of the Korotkoff phases of blood pressure in children.
TL;DR: Insight is provided into the problems of accurate diastolic blood pressure measurement by providing data on the repeatability of these measurements, the relationship between the phases, and finally the relationshipBetween the phases and heart rate, blood pressure and arm circumference.
Control of Gene Expression by Redox Potential and the Requirement for Chloroplast and Mitochondrial Genomes
TL;DR: Chloroplast and mitochondrial redox sensors and redox response regulators, themselves encoded in the nucleus, may place expression of chloropleft and mitochondrial genes under redox regulatory control, and this hypothesis offers an explanation for the persistence of chloroplasts and mitochondrial genomes and for the constancy of the subset of chloroform and mitochondrial proteins encoded and synthesized within the organelle.
•Journal Article
Breast cancer resistance protein is localized at the plasma membrane in mitoxantrone- and topotecan-resistant cell lines.
George L. Scheffer,Marc Maliepaard,Aclm Pijnenborg,M A van Gastelen,A. B. Schroeijers,John F. Allen,Douglas D. Ross,P. van der Valk,William S. Dalton,J.H.M. (Jan) Schellens,R.J. Scheper,M C de Jong +11 more
TL;DR: A BCRP-specific monoclonal antibody is described, obtained from mice, immunized with mitoxantrone-resistant, B CRP mRNA-positive MCF-7 MR human breast cancer cells, and pronounced staining of the cell membranes showed that the transporter is mainly present at the plasma membrane.
Pim-2 transgene induces lymphoid tumors, exhibiting potent synergy with c-myc.
TL;DR: The addition of pim-2 to the fold increases the prominence of the pim proto-oncogene family in tumorigenesis in mice manifested as pre-B cell leukemia in neonate bi-transgenic animals.