John D. Frame
Columbia University
15 Papers
255 Citations
John D. Frame is an academic researcher from Columbia University. The author has contributed to research in topics: Lassa fever & Lassa virus. The author has an hindex of 14, co-authored 15 publications.
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Papers
Endemic Lassa fever in Liberia. IV. Selection of optimally effective plasma for treatment by passive immunization.
TL;DR: Cross serological testing with LV strains and convalescent plasma from patients in Sierra Leone, Liberia and Nigeria suggested that these LV strains were indistinguishable by cross-IFA, but were readily distinguishable by cross neutralization tests.
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Clinical Features of Lassa Fever in Liberia
TL;DR: A great variation in mortality and incidence of abnormal bleeding is recorded in reported series of LF; it appears that hemorrhage is a marker for cases with a high mortality.
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Pediatric Lassa fever: a review of 33 Liberian cases.
Mark H. Monson,Andrew K. Cole,John D. Frame,Janet R. Serwint,Suzama Alexander,Peter B. Jahrling +5 more
TL;DR: A "swollen baby syndrome" consisting of widespread edema, abdominal distention, and bleeding was present in three of the four childhood deaths in this series and seems to be a good prognostic indicator in children.
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Endemic Lassa fever in Liberia. I. Clinical and epidemiological aspects at Curran Lutheran Hospital, Zorzor, Liberia
TL;DR: A previously unreported symptom of LF, rib tenderness typical of costochondritis, is found, which is common at CLH, and as many as 100 cases may occur annually at this hospital.
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Lassa fever virological and serological studies
TL;DR: Sero-epidemiological studies indicate that Lassa virus infection occurs over a wide area of western Africa extending at least from Guinea to Nigeria, where it was isolated from specimens collected from patients involved in an epidemic of LassA Fever which occurred in Jos during 1970.
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