John Cullum
Kaiserslautern University of Technology
68 Papers
609 Citations
John Cullum is an academic researcher from Kaiserslautern University of Technology. The author has contributed to research in topics: Plasmid & Biology. The author has an hindex of 23, co-authored 68 publications.
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Papers
ClustScan: an integrated program package for the semi-automatic annotation of modular biosynthetic gene clusters and in silico prediction of novel chemical structures
TL;DR: The program package ‘ClustScan’ (Cluster Scanner) is designed for rapid, semi-automatic, annotation of DNA sequences encoding modular biosynthetic enzymes including polyketide synthases, non-ribosomal peptide synthetases and hybrid (PKS/NRPS) enzymes.
Physical map of the Streptomyces lividans 66 genome and comparison with that of the related strain Streptomyces coelicolor A3(2).
TL;DR: A physical map of the chromosome of Streptomyces lividans 66 ZX7 was constructed by ordering the macrorestriction fragments generated from the genomic DNA with the restriction enzymes AseI and DraI, revealing a common structure with an identical ordering of the cosmid sequences.
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Enzymes of the shikimic acid pathway encoded in the genome of a basal metazoan, Nematostella vectensis, have microbial origins
Antonio Starcevic,Shamima Akthar,Walter C. Dunlap,J. Malcolm Shick,Daslav Hranueli,John Cullum,Paul F. Long +6 more
TL;DR: A complementary view for the biogenesis of shikimate-related metabolites in marine Cnidaria as a “shared metabolic adaptation” between the partners is provided.
The Streptomyces lividans 66 chromosome contains a 1 MB deletogenic region flanked by two amplifiable regions.
Matthias Redenbach,Fiona Flett,Wolfang Piendl,Ingrun Glocker,Uwe Rauland,Oliver Wafzig,Ralf Kliem,Pierre Leblond,John Cullum +8 more
TL;DR: Overlapping cosmids were isolated that span the ca.
83
The 387 kb linear plasmid pPZG101 of Streptomyces rimosus and its interactions with the chromosome.
TL;DR: The linear plasmid pPZG101 of Streptomyces rimosus R6 was restriction mapped with the enzymes AseI, BfrI, DraI and XbaI and it suggested that at least three of the integrated strains had retained free plasmids ends.