John Caird
Temple University
27 Papers
22 Citations
John Caird is an academic researcher from Temple University. The author has contributed to research in topics: Medicine & Glioma. The author has an hindex of 5, co-authored 21 publications. Previous affiliations of John Caird include Beaumont Hospital & Royal College of Surgeons in Ireland.
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Papers
Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma
Alan Mackay,Anna Burford,Diana Carvalho,Elisa Izquierdo,Janat Fazal-Salom,Kathryn R. Taylor,Kathryn R. Taylor,Lynn Bjerke,Matthew Clarke,Mara Vinci,Meera Nandhabalan,Sara Temelso,Sergey Popov,Sergey Popov,Valeria Molinari,Pichai Raman,Angela J. Waanders,Harry J. Han,Saumya Gupta,Lynley V. Marshall,Stergios Zacharoulis,Sucheta Vaidya,Henry Mandeville,Leslie R. Bridges,Andrew J. Martin,Safa Al-Sarraj,Christopher Chandler,Ho Keung Ng,Xingang Li,Kun Mu,Saoussen Trabelsi,Dorra H'mida-Ben Brahim,Alexei N. Kisljakov,Dmitry M. Konovalov,Andrew S. Moore,Angel M. Carcaboso,Mariona Suñol,Carmen Torres,Ofelia Cruz,Jaume Mora,Ludmila I. Shats,João Norberto Stávale,Lucas Tadeu Bidinotto,Rui Manuel Reis,Natacha Entz-Werle,Michael A. Farrell,Jane Cryan,Darach Crimmins,John Caird,Jane Pears,Michelle Monje,Marie-Anne Debily,David Castel,Jacques Grill,Cynthia Hawkins,Hamid Nikbakht,Nada Jabado,Suzanne J. Baker,Stefan M. Pfister,Stefan M. Pfister,David T.W. Jones,Maryam Fouladi,André O. von Bueren,André O. von Bueren,Michael Baudis,Adam C. Resnick,Chris Jones +66 more
TL;DR: Genomic aberrations increase with age, highlighting the infant population as biologically and clinically distinct, and co-segregating mutations in histone-mutant subgroups including loss of FBXW7 in H 3.3G34R/V, TOP3A rearrangements in H3.3K27M, and BCOR mutations in H2.1K 27M are identified.
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Indirect cavernous carotid fistula in a 12-year-old girl.
TL;DR: CCF, though rare in the paediatric population, should be highly considered in the differential diagnosis when dilated scleral veins, proptosis and dysdiadokinesis are present in the clinical setting.
Thinking outside the shunt—sterile CSF malabsorption in pilocytic astrocytomas: case series and review of the literature
TL;DR: Two paediatric cases diagnosed with suprasellar pilocytic astrocytomas treated with platinum-based chemotherapy, who subsequently developed sterile CSF ascites are discussed and CSF malabsorption with resultant ascites is discussed as a contributing factor to shunt malfunction.
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Prenatal findings and associated survival rates in fetal ventriculomegaly: A prospective observational study
Gillian A. Ryan,Alex O. Start,Barbara Cathcart,Heather Hughes,Branko Denona,Shane Higgins,Siobhan Corcoran,Jennifer M. Walsh,Stephen Carroll,Rhona Mahony,Darach Crimmins,John Caird,Ian Robinson,Gabrielle C. Colleran,Peter McParland,Fionnuala M. McAuliffe +15 more
TL;DR: Ventriculomegaly is a complex condition and patients should be counselled that even with apparently isolated VM, there remains the possibility of additional genetic and/or structural problems being diagnosed in up to 10% of fetuses.
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Drug screening linked to molecular profiling identifies novel dependencies in patient-derived primary cultures of paediatric high grade glioma and DIPG
Diana Carvalho,Sara Temelso,Alan Mackay,Helen N. Pemberton,Rebecca Rogers,Ketty Kessler,Elisa Izquierdo,Lynn Bjerke,Janat Fazal Salom,Matthew Clarke,Yura Grabovska,Anna Burford,Nagore G. Olaciregui,Jessica K.R. Boult,Valeria Molinari,Mariama Fofana,Paula Proszek,Elisabet F Potente,Kathryn R. Taylor,Kathryn R. Taylor,Christopher Chandler,Bassel Zebian,Ranj Bhangoo,Andrew J. Martin,Bassam Dabbous,Simon R. Stapleton,Samantha Hettige,Lynley V. Marshall,Lynley V. Marshall,Fernando Carceller,Fernando Carceller,Henry Mandeville,Sucheta Vaidya,Safa Al-Sarraj,Leslie R. Bridges,Robert Johnston,Jane Cryan,Michael Farrell,Darach Crimmins,John Caird,Jane Pears,Giulia Pericoli,Evelina Miele,Angela Mastronuzzi,Franco Locatelli,Andrea Carai,Simon P. Robinson,Mike Hubank,Michelle Monje,Andrew S. Moore,Andrew S. Moore,Timothy E.G. Hassall,Timothy E.G. Hassall,Timothy E.G. Hassall,Angel M. Carcaboso,Christopher J. Lord,Mara Vinci,Chris Jones +57 more
TL;DR: In this paper, the authors present 17 primary cell cultures derived from patients in London, Dublin and Belfast, and together with cultures established or shared from Barcelona, Brisbane, Rome and Stanford, assembled a panel of 52 models under 2D (laminin matrix) and/or 3D (neurospheres) conditions.
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