Johannes Levin
18 Papers
Johannes Levin is an academic researcher. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 3, co-authored 6 publications.
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Papers
Distinct molecular profiles of skull bone marrow in health and neurological disorders
Z. I. Kolabas,L. B. Kuemmerle,Robert Perneczky,Benjamin Förstera,Selin Ulukaya,Mayar Ali,Saketh Kapoor,L. Bartos,Maren Büttner,Ozum S. Caliskan,Zhouyi Rong,Hongcheng Mai,Luciano Höher,Denise Jeridi,Muge Molbay,Igor Khalin,I.K. Deligiannis,Moritz Negwer,Kenny Roberts,Alba Simats,O Carofiglio,Mihail Ivilinov Todorov,Izabela Horvath,Furkan Ozturk,Selina Hummel,Gloria Biechele,A.V Zatcepin,Marcus Unterrainer,Johannes Gnörich,Jay Roodselaar,Joshua Shrouder,Pardis Khosravani,Benjamin Tast,Lisa Richter,Laura Díaz-Marugán,Doris Kaltenecker,Laurin Lux,Ying Chen,Shan Zhao,Boris-Stephan Rauchmann,Michael Sterr,I. Kunze,Karen Stanic,Vanessa W. Y. Kan,S. Besson-Girard,Sabrina Katzdobler,Carla Palleis,Julia Schädler,Johannes C. Paetzold,Sabine Liebscher,Anja E. Hauser,Ozgun Gokce,Heiko Lickert,Hanno Steinke,Corinne Benakis,Christian Braun,Celia P. Martinez-Jimenez,Katharina Buerger,Nathalie L. Albert,Günter U. Höglinger,Johannes Levin,Christian Haass,Anna Kopczak,Martin Dichgans,Joachim Havla,Tania Kümpfel,Martin Kerschensteiner,Martina Schifferer,Mikael Simons,Arthur Liesz,Natalie Krahmer,Omer Ali Bayraktar,Nicolai Franzmeier,Nikolaus Plesnila,Suheda Erener,Victor G. Puelles,Claire Delbridge,Harsharan S. Bhatia,Farida Hellal,Markus Elsner,Ingo Bechmann,Benjamin Ondruschka,Matthias Brendel,Fabian J. Theis,Ali Erturk +84 more
TL;DR: The mouse skull has the most distinct transcriptomic profile compared with other bones in states of health and injury, characterized by a late-stage neutrophil phenotype, and the unique molecular profile and anatomical and functional connections of the skull show its potential as a site for diagnosing, monitoring, and treating brain diseases.
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The Unified Multiple System Atrophy Rating Scale: Status, Critique, and Recommendations
Florian Krismer,José M. Palma,Giovanna Calandra-Buonaura,Ivan Stankovic,Luca Vignatelli,Anna-Karin Berger,Cristian Falup-Pecurariu,Alexandra Foubert-Samier,Günter U. Höglinger,Horacio Kaufmann,Larry Kellerman,Han Joon Kim,Thomas Klockgether,Johannes Levin,Pablo Martinez-Martin,Tiago A. Mestre,Maria Teresa Pellecchia,Susan Perlman,Irfan A. Qureshi,Olivier Rascol,Anette Schrag,Klaus Seppi,Huifang Shang,Glenn T. Stebbins,Gregor K. Wenning,Wolfgang Singer,Wassilios G. Meissner +26 more
TL;DR: Florian Krismer, MD, PhD, Jose-Alberto Palma et al. as discussed by the authors , MD, Dr. Sebastiani et al., MD, and Dr. Meissner.
Common Variants Near ZIC1 and ZIC4 in Autopsy‐Confirmed Multiple System Atrophy
Franziska Hopfner,Anja K Tietz,Viktoria Ruf,Owen A. Ross,Shunsuke Koga,Dennis W. Dickson,Adriano Aguzzi,Johannes Attems,Thomas G. Beach,Allison Beller,William P. Cheshire,Vivianna M. Van Deerlin,Paula Desplats,Günther Deuschl,Charles Duyckaerts,David Ellinghaus,Valentin Evsyukov,Margaret E. Flanagan,Andre Franke,Matthew P. Frosch,Marla Gearing,Ellen Gelpi,Jay A. van Gerpen,Bernardino Ghetti,Jonathan D. Glass,Lea T. Grinberg,Glenda M. Halliday,Ingo Helbig,Matthias Höllerhage,Inge Huitinga,David J. Irwin,Dirk C. Keene,Gabor G. Kovacs,Edward B. Lee,Johannes Levin,María José Martí,Ian R. A. Mackenzie,Ian G. McKeith,Catriona McLean,Brit Mollenhauer,Manuela Neumann,Kathy Newell,Alexander Pantelyat,Manuela Pendziwiat,Annette Peters,Laura Molina Porcel,Alberto Rábano,Radoslav Matej,Alex Rajput,Ali H. Rajput,Regina Reimann,William K. Scott,William W. Seeley,Sashika Selvackadunco,Tanya Simuni,Christine Stadelmann,Per Svenningsson,Alan J. Thomas,Claudia Trenkwalder,Claire Troakes,John Q. Trojanowski,Ryan J. Uitti,Charles L. White,Zbigniew K. Wszolek,Tao Xie,Teresa Ximelis,Justo García de Yébenes,K. Müller,Gerard D. Schellenberg,Jochen Herms,Gregor Kuhlenbäumer,Günter U. Höglinger +71 more
TL;DR: One prior genome‐wide association study in mainly clinically diagnosed patients with Multiple System Atrophy failed to identify genetic variants predisposing for the disease.
Longitudinal clinical, cognitive, and biomarker profiles in dominantly inherited versus sporadic early-onset Alzheimer’s disease.
Jorge J. Llibre-Guerra,Leonardo Iaccarino,Dean W. Coble,Lauren Edwards,Yan Li,Eric McDade,Amelia Strom,Brian A. Gordon,N. Mundada,Suzanne E. Schindler,Elena Tsoy,Yinjiao Ma,Ruijin Lu,Anne M Fagan,Tammie L.S. Benzinger,David N Soleimani-Meigooni,Andrew J. Aschenbrenner,Zachary A. Miller,Guoqiao Wang,Joel H Kramer,Jason Hassenstab,Howard J. Rosen,John C Morris,Bruce L. Miller,Chengjie Xiong,R. Perrino,Ricardo F. Allegri,Patricio Chrem,Ezequiel Surace,Sarah B. Berman,Jasmeer P. Chhatwal,C. L. Masters,Marty Farlow,Mathias Jucker,Johannes Levin,Nick C. Fox,Gregory S. Day,Maria Luisa Gorno-Tempini,Adam L. Boxer,Renaud La Joie,Gil D Rabinovici,Randall J. Bateman +41 more
TL;DR: Sporadic early onset is best distinguished from dominantly inherited by later age at onset, high frequency of atypical clinical presentations and worse executive performance at baseline, and shared pathways in longitudinal clinical decline and CSF biomarkers suggest potential common therapeutic targets for both populations.
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Location of pathogenic variants in PSEN1 impacts progression of cognitive, clinical, and neurodegenerative measures in autosomal-dominant Alzheimer's disease.
Stephanie A. Schultz,Zahra Shirzadi,L. Schultz,Lei Li,Colleen D. Fitzpatrick,Eric McDade,Nicolas R. Barthélemy,Alan E. Renton,Bianca Esposito,Nelly Joseph-Mathurin,Carlos Cruchaga,Charles Chen,Alison Goate,Ricardo F. Allegri,Tammie L.S. Benzinger,Sarah B. Berman,Helena C. Chui,Anne M. Fagan,Martin R. Farlow,Nick C. Fox,Brian A. Gordon,Gregory S. Day,Neill R. Graff-Radford,Jason Hassenstab,Bernard Hanseeuw,Anna Hofmann,Clifford R. Jack,Mathias Jucker,Celeste M. Karch,Robert A. Koeppe,Jae-Hong Lee,Allan I. Levey,Johannes Levin,Ralph N. Martins,Hiroshi Mori,John C. Morris,James M. Noble,R. Perrino,Pedro Rosa-Neto,Stephen Salloway,Raquel Sánchez-Valle,Peter R. Schofield,Chengjie Xiong,Keith A. Johnson,Randall J. Bateman,Reisa A. Sperling,Jasmeer P. Chhatwal +46 more
TL;DR: In this paper , the authors hypothesized that the interindividual variability may be associated with the location of the pathogenic variant within PSEN1, and they used linear mixed effects models to determine differences in clinical, cognitive, and biomarker measures between the NC, TM, and CY groups.
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