Jocelyne Jacquemier
French Institute of Health and Medical Research
248 Papers
3.3K Citations
Jocelyne Jacquemier is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Breast cancer & Cancer. The author has an hindex of 78, co-authored 241 publications. Previous affiliations of Jocelyne Jacquemier include University Hospital of Basel.
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Papers
ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome.
Christophe Ginestier,Min Hee Hur,Emmanuelle Charafe-Jauffret,Florence Monville,Julie Dutcher,Marty Brown,Jocelyne Jacquemier,Patrice Viens,Celina G. Kleer,Suling Liu,Anne F. Schott,Daniel F. Hayes,Daniel Birnbaum,Max S. Wicha,Gabriela Dontu +14 more
TL;DR: It is shown that normal and cancer human mammary epithelial cells with increased aldehyde dehydrogenase activity (ALDH) have stem/progenitor properties and these cells contain the subpopulation of normal breast epithelium with the broadest lineage differentiation potential and greatest growth capacity in a xenotransplant model.
4.1K
The Pathology of Familial Breast Cancer: Predictive Value of Immunohistochemical Markers Estrogen Receptor, Progesterone Receptor, HER-2, and p53 in Patients With Mutations in BRCA1 and BRCA2
Sunil R. Lakhani,Marc J. van de Vijver,Jocelyne Jacquemier,Thomas J. Anderson,Peter Osin,Lesley McGuffog,Douglas F. Easton +6 more
TL;DR: The combined morphologic and immunohistochemical data can be used to predict the risk of a young patient harboring a germline mutation in BRCA1, and the BRC a2 phenotype is currently not well defined.
Comparative study of the National Cancer Institute and French Federation of Cancer Centers Sarcoma Group grading systems in a population of 410 adult patients with soft tissue sarcoma
Louis Guillou,J.-M. Coindre,Françoise Bonichon,B. Bui Nguyen,P. Terrier,F. Collin,Marie-Odile Vilain,A. M. Mandard,V Le Doussal,A. Leroux,Jocelyne Jacquemier,H Duplay,Xavier Sastre-Garau,J Costa +13 more
TL;DR: The FNCLCC system showed slightly increased ability to predict distant metastasis development and tumor mortality, and the use of this system to evaluate STS aggressiveness might be favored.
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Aldehyde Dehydrogenase 1–Positive Cancer Stem Cells Mediate Metastasis and Poor Clinical Outcome in Inflammatory Breast Cancer
Emmanuelle Charafe-Jauffret,Christophe Ginestier,Flora Iovino,Carole Tarpin,Mark E. Diebel,Benjamin Esterni,Gilles Houvenaeghel,Jean-Marc Extra,François Bertucci,François Bertucci,Jocelyne Jacquemier,Luc Xerri,Luc Xerri,Gabriela Dontu,Giorgio Stassi,Yi Xiao,Sanford H. Barsky,Daniel Birnbaum,Patrice Viens,Max S. Wicha +19 more
TL;DR: AlDH1 expression represents the first independent prognostic marker to predict metastasis and poor patient outcome in IBC and suggests that the metastatic, aggressive behavior of IBC may be mediated by a CSC component that displays ALDH enzymatic activity.
791
Basal-like and triple-negative breast cancers: a critical review with an emphasis on the implications for pathologists and oncologists
Sunil Badve,David J. Dabbs,Stuart J. Schnitt,Frederick L. Baehner,Thomas Decker,Vincenzo Eusebi,Stephen B. Fox,Shu Ichihara,Jocelyne Jacquemier,Sunil R. Lakhani,José Palacios,Emad A. Rakha,Andrea L. Richardson,Fernando Schmitt,Puay Hoon Tan,Gary Tse,Britta Weigelt,Ian O. Ellis,Jorge S. Reis-Filho +18 more
TL;DR: The purpose of this article was to discuss the relationship between basal-like and triple-negative breast cancers, and to clarify practical implications of these diagnoses for pathologists and oncologists.
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