Jocelyn C Ray
National Institutes of Health
7 Papers
1 Citations
Jocelyn C Ray is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Neisseria gonorrhoeae & Medicine. The author has an hindex of 3, co-authored 4 publications.
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Papers
HIV Envelope gp120 Alters T Cell Receptor Mobilization in the Immunological Synapse of Uninfected CD4 T Cells and Augments T Cell Activation.
Jing Deng,Yu-ya Mitsuki,Guomiao Shen,Jocelyn C Ray,Claudia Cicala,James Arthos,Michael L. Dustin,Michael L. Dustin,Catarina E. Hioe +8 more
TL;DR: The results suggest that HIV uses the immunological synapse as a conduit not only for selective virus transmission to activated CD4 T cells but also for boosting the T cell activation state, thereby increasing its likelihood of undergoing productive replication in targeted CD 4 T cells.
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Neisseria gonorrhoeae co-opts C4b-binding protein to enhance complement-independent survival from neutrophils
Lacie M. Werner,Allison M. Alcott,Frida C. Mohlin,Jocelyn C Ray,Meagan Belcher Dufrisne,Asya Smirnov,Linda Columbus,Anna M. Blom,Alison K. Criss +8 more
TL;DR: In this article , a complement-independent function for C4b-binding protein (C4BP) was found to be necessary and sufficient to suppress Gc-induced neutrophil reactive oxygen species production.
•Journal Article
MAdCAM signaling through integrin α4β7 modulates surface expression of CCR5 and markers of CD4+ T cell activation.
Ian Perrone,Claudia Cicala,Fatima Nawaz,Jocelyn C Ray,Ronke Olowojesiku,Mia Waliszewski,Katija Jelicic,Danlan Wei,Donald Van Ryk,Aftab A. Ansari,Anthony S. Fauci,James Arthos +11 more
TL;DR: The response of α 4 β 7 + /CD4 + T cells to costimulation via MAdCAM is characterized to better understand whether the induced phenotype would support an enhanced degree of viral replication.
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Metal piracy by Neisseria gonorrhoeae to overcome human nutritional immunity
TL;DR: The bacterium Neisseria gonorrhoeae causes the sexually transmitted disease gonorrhea, which is an obligate human pathogen that colonizes mucosal surfaces of the urogenital tract, pharynx, rectum as discussed by the authors .
MAdCAM costimulation through Integrin-α4β7 promotes HIV replication.
Fatima Nawaz,Livia R. Goes,Jocelyn C Ray,Ronke Olowojesiku,Alia Sajani,Aftab A. Ansari,Ian Perrone,Joseph Hiatt,Donald Van Ryk,Danlan Wei,Mia Waliszewski,Marcelo A. Soares,Katija Jelicic,Mark Connors,Stephen A. Migueles,Elena Martinelli,Francois Villinger,Claudia Cicala,Anthony S. Fauci,James Arthos +19 more
TL;DR: It is reported here that MAdCAM delivers a potent costimulatory signal to naive and memory CD4+ T cells following ligation with α4β7, which promotes high levels of HIV replication and highlights the potential of such agents to control acute HIV infection.