Jiyon Lee
Konkuk University
7 Papers
25 Citations
Jiyon Lee is an academic researcher from Konkuk University. The author has contributed to research in topics: Apoptosis & Cell cycle checkpoint. The author has an hindex of 3, co-authored 7 publications.
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Papers
Calotropis gigantea extract induces apoptosis through extrinsic/intrinsic pathways and reactive oxygen species generation in A549 and NCI-H1299 non-small cell lung cancer cells
Jiyon Lee,Hui-Ju Jang,Hyun-Woo Chun,Thu-Huyen Pham,Yesol Bak,Jong-Woon Shin,Hang Jin,Yong-In Kim,Hyung Won Ryu,Sei-Ryang Oh,Do-Young Yoon +10 more
TL;DR: It is confirmed that CG caused apoptosis through the activation of extrinsic and intrinsic pathways, cell cycle arrest, and ROS generation in A549 and NCI-H1299 lung cancer cells, which can be suggested as a potential agent for lung cancer therapy.
Differential effects of luteolin and its glycosides on invasion and apoptosis in MDA-MB-231 triple-negative breast cancer cells
Jiyon Lee,Su-Ho Park,Jintak Lee,Hyun-Woo Chun,Myoung-Kwon Choi,Jae-Hwan Yoon,Thu-Huyen Pham,Ki Hong Kim,Taeho Kwon,Hyung-Won Ryu,Sei-Ryang Oh,Do-Young Yoon +11 more
TL;DR: Luteolin had both antimetastatic and cytotoxic effects on MDA-MB-231 cells, whereas luteolin glycosides had no effect on this cell line, which can be suggested as a potential candidate for breast cancer therapy.
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Resolvin D5, a Lipid Mediator, Inhibits Production of Interleukin-6 and CCL5 Via the ERK-NF-κB Signaling Pathway in Lipopolysaccharide-Stimulated THP-1 Cells.
Hyun-Woo Chun,Jintak Lee,Pham Thu Huyen,Jiyon Lee,Jae-Hwan Yoon,Jin Lee,Deok-Kun Oh,Jae-Wook Oh,Do-Young Yoon +8 more
TL;DR: Investigation of the effects of resolvin D5 on inflammation-related signaling pathways, including the extracellular signal-regulated kinase (ERK)-nuclear factor (NF)-κB signaling pathway, revealed that it exerts anti-inflammatory effects in LPS-treated THP-1 cells by regulating the phosphorylation of ERK and nuclear translocation of NF-κB.
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Methyl linderone suppresses TPA-stimulated IL-8 and MMP-9 expression via the ERK/STAT3 pathway in MCF-7 breast cancer cells
Jae-Hwan Yoon,Thu-Huyen Pham,Jintak Lee,Jiyon Lee,Hyung-Won Ryu,Sei-Ryang Oh,Jae-Wook Oh,Do-Young Yoon +7 more
TL;DR: It is indicated that ML attenuated the TPA-stimulated invasion and migration of MCF-7 cells by suppressing the phosphorylation of ERK and its downstream factors, AP-1 and STAT3, which is a potential agent for the treatment of breast cancer metastasis.
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Kanakugiol, a Compound Isolated from Lindera erythrocarpa, Promotes Cell Death by Inducing Mitotic Catastrophe after Cell Cycle Arrest.
Jintak Lee,Hyun-Woo Chun,Thu-Huyen Pham,Jae-Hwan Yoon,Jiyon Lee,Myoung-Kwon Choi,Hyung-Won Ryu,Sei-Ryang Oh,Jae-Wook Oh,Do-Young Yoon +9 more
TL;DR: It is suggested that kanakugiol inhibits cell proliferation and promotes cell death by inducing mitotic catastrophe after cell cycle arrest and shows potential for use as a drug in the treatment of human breast cancer.
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