5 Papers
6 Citations
Jiye Chen is an academic researcher from Shandong University of Traditional Chinese Medicine. The author has contributed to research in topics: Medicine & Gut flora. The author has an hindex of 1, co-authored 2 publications.
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Papers
The crosstalk between NLRP3 inflammasome and gut microbiome in atherosclerosis.
TL;DR: In this paper , the interaction between the NLRP3 inflammasome and the Gut Microbiome and its metabolites was studied for the treatment of the AS. But, the authors focused on the interaction of the Inflammasomes and the intestinal micro-ecology, which plays an important role in the development of AS.
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Xiao-Qing-Long Tang Prevents Cardiomyocyte Hypertrophy, Fibrosis, and the Development of Heart Failure with Preserved Ejection Faction in Rats by Modulating the Composition of the Gut Microbiota.
Guofeng Zhou,Yue-Hua Jiang,Du-Fang Ma,Yongcheng Wang,Jinlong Yang,Jiye Chen,Chen-Yu Chi,Xiao-wei Han,Zhao-Yu Li,Xiao Li +9 more
TL;DR: It is suggested that XQLT prevented the development of HFpEF in model rats by regulating the composition of the gut microbiota.
Targets of statins intervention in LDL-C metabolism: Gut microbiota
TL;DR: The interaction between gut microbiota and cholesterol metabolism, especially the cholesterol-lowering effect of statins mediated by gut microbiota, is discussed, via AMPK-PPARγ-SREBP1C/2, FXR and PXR-related, and LPS-TLR4-Myd88 pathways, which may help to explain the individual differences in statins efficacy.
Potential mechanisms of Guizhi decoction against hypertension based on network pharmacology and Dahl salt-sensitive rat model.
Jiye Chen,Yongjian Zhang,Yongcheng Wang,Ping Jiang,Guofeng Zhou,Zhao-Yu Li,Jinlong Yang,Xiao Li +7 more
TL;DR: Guizhi decoction (GZD) has been widely used to treat hypertension, but its underlying mechanisms remain elusive as discussed by the authors, which aims to explore the potential mechanisms and therapeutic effects of GZD on hypertension by integrating network pharmacology and experimental validation.
Protective effects of paeoniflorin on cardiovascular diseases: A pharmacological and mechanistic overview
Xiaoya Li,Changxin Sun,Jing Zhang,Lanqing Hu,Zongliang Yu,Xiaonan Zhang,Zeping Wang,Jiye Chen,Min Wu,Longtao Liu +9 more
TL;DR: Paeoniflorin (5beta-[(Benzoyloxy)methyl] tetrahydro-5-hydroxy-2-methyl-2,5-methano-1H-3,4-dioxacyclobuta [cd] pentalen-1alpha (2H)-yl-beta-D-glucopyranoside, C23H28O11) is mostly derived from the plants of the family Paeoniaceae (a single genus family) and is known to possess multiple pharmacological properties in the treatment of cardiovascular diseases, making it a promising agent for the protection of the cardiovascular system as discussed by the authors .