Jiwon Lee
University of Toronto
13 Papers
32 Citations
Jiwon Lee is an academic researcher from University of Toronto. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 2, co-authored 4 publications. Previous affiliations of Jiwon Lee include Centre for Addiction and Mental Health.
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Papers
Evolution of Drosophila sex comb length illustrates the inextricable interplay between selection and variation
Juan Nicolas Malagon,Abha Ahuja,Gabilan Sivapatham,Julian Hung,Jiwon Lee,Sergio A. Muñoz-Gómez,Joel Atallah,Rama S. Singh,Ellen Larsen +8 more
TL;DR: The sex comb is studied, a group of modified bristles used in courtship that shows marked morphological diversity among Drosophila species, to find that artificial selection changes the number of bristles per comb without a proportional change in the space available for rotation.
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Pharmacological Interventions to Treat Antipsychotic-Induced Dyslipidemia in Schizophrenia Patients: A Systematic Review and Meta Analysis.
Pruntha Kanagasundaram,Jiwon Lee,Jiwon Lee,Femin Prasad,Femin Prasad,Kenya A. Costa-Dookhan,Kenya A. Costa-Dookhan,Laurie Hamel,Madeleine Gordon,Gary Remington,Gary Remington,Margaret Hahn,Sri Mahavir Agarwal +12 more
TL;DR: In this paper, the effectiveness of pharmacological interventions in alleviating dyslipidemia in patients with schizophrenia was evaluated in 48 randomized controlled trials that comprised a total of 3,128 patients.
Metabolomic signatures associated with weight gain and psychosis spectrum diagnoses: A pilot study
Jiwon Lee,Kenya A. Costa-Dookhan,Nicole E. MacKenzie,Quinn Casuccio Treen,Araba Chintoh,Gary Remington,Daniel J. Müller,Sanjeev Sockalingam,Philip Gerretsen,Marcos Sanches,Alla Karnovsky,K. Stringer,Vicki L. Ellingrod,Ivy F. Tso,Stephan F. Taylor,Sri Mahavir Agarwal,Margaret Hahn,Kristen M. Ward +17 more
TL;DR: In this article , the authors examined changes in metabolomic profiles over 12 weeks of antipsychotic treatment to identify metabolites that may associate with AP-induced weight gain, and they also compared baseline metabolomes of participants who gained ≥ 5% baseline body weight to those who gained <5% to identify potential biomarkers of antippsychotic induced weight gain.
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•Journal Article
Using a Model Organism to Infer Mechanisms of Morphological Evolution: the Case of Fly Sex Combs
TL;DR: The results suggest that mutations in one species can mimic aspects of sex comb patterns in other species, and that there may be a basic “ground plan” in developing tarsal segments that can be rather rapidly shifted in evolution.
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Glucose dysregulation in antipsychotic-naive first-episode psychosis: in silico exploration of gene expression signatures
Jiwon Lee,Xiangning Xue,Emily Ka-Lei Au,William B McIntyre,Roshanak Asgariroozbehani,Kristoffer Panganiban,George C. Tseng,Maria Papoulias,E. Smith,Jonathan Monteiro,Divia Shah,Kateryna Maksyutynska,Samantha Cavalier,Emril Radoncic,Femin Prasad,Sri Mahavir Agarwal,Robert Mccullumsmith,Zachary Freyberg,Ryan Logan,Margaret K Hahn +19 more
TL;DR: These data suggest that the pathobiology of PSDs overlaps and potentially contributes to dysglycemia, and find that metformin may be a potential treatment for early metabolic dysfunction intrinsic to PSDs.
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