Jinyun Wu
Fudan University
6 Papers
7 Citations
Jinyun Wu is an academic researcher from Fudan University. The author has contributed to research in topics: Regulation of gene expression & Recombinase. The author has an hindex of 2, co-authored 6 publications.
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Papers
Transcardiac Perfusion of the Mouse for Brain Tissue Dissection and Fixation
Jinyun Wu,Yu-Qi Cai,Xiao-Yang Wu,Yue Ying,Yilin Tai,Miao He +5 more
- 05 Mar 2021
TL;DR: In this article, a step by step guide for performing transcardiac perfusion with saline followed by 4% paraformaldehyde (PFA) is provided for performing in mouse.
microRNA Deficiency in VIP+ Interneurons Leads to Cortical Circuit Dysfunction.
Fang Qiu,Xingfeng Mao,Penglai Liu,Jinyun Wu,Yuan Zhang,Daijing Sun,Yueyan Zhu,Ling Gong,Mengmeng Shao,Keyang Fan,Junjie Chen,Jiangteng Lu,Yan Jiang,Yubin Zhang,Giulia Curia,Anan Li,Miao He +16 more
TL;DR: It is found that the intrinsic and synaptic properties of VIP+ interneurons and pyramidal neurons were concordantly affected prior to a progressive loss of VIP+, and elevated cortical local field potential power was revealed.
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Topographical organization of mammillary neurogenesis and efferent projections in the mouse brain.
Yongjie Hou,Qi Zhang,Hongzhi Liu,Jinyun Wu,Yun Shi,Yanqing Qi,Mengmeng Shao,Zhengang Yang,Jiangteng Lu,Zhuhao Wu,Ling Gong,Miao He +11 more
TL;DR: In this article, the authors identify progenitor-specific Fezf2 expression in the developing mammillary body and develop an intersectional fate-mapping approach to demonstrate that mammillary progenitors generate mammillary neurons in a rostral-dorsal-lateral to caudal-ventral-medial fashion.
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Viral approaches to study the mammalian brain: Lineage tracing, circuit dissection and therapeutic applications
TL;DR: The most commonly used viruses for these applications and some recent advances in improving the resolution and throughput of lineage tracing, the efficacy and selectivity of circuit tracing and the specificity of cell type targeting are introduced.
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Emerging strategies for the genetic dissection of gene functions, cell types, and neural circuits in the mammalian brain.
TL;DR: In this paper, a review of strategies for gene regulation on DNA, RNA, and protein levels and their applications in cell type targeting and neural circuit dissection is presented. And the potential caveats and pitfalls in current methods and suggest future prospects to improve their comprehensiveness and versatility.
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