Jinru Shia
Memorial Sloan Kettering Cancer Center
405 Papers
1.4K Citations
Jinru Shia is an academic researcher from Memorial Sloan Kettering Cancer Center. The author has contributed to research in topics: Medicine & Colorectal cancer. The author has an hindex of 81, co-authored 332 publications. Previous affiliations of Jinru Shia include Kettering University & Cornell University.
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Papers
Primary peritoneal mesothelioma: How aggressive should we be?
TL;DR: Long-term survival can be realized in patients that undergo optimal debulking, without peritonectomy, and receive adjuvant i.p. chemotherapy, as compared to those who were sub-optimally debulked.
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Same-Cell Co-Occurrence of RAS Hotspot and BRAF V600E Mutations in Treatment-Naive Colorectal Cancer
Rodrigo Gularte-Mérida,Shaleigh Smith,Anita S. Bowman,Arnaud Da Cruz Paula,Walid K. Chatila,Craig M. Bielski,Monika Vyas,Laetitia Borsu,Ahmet Zehir,Luciano G. Martelotto,Jinru Shia,Rona Yaeger,Fang Fang,Rui Gardner,Ruibang Luo,Michael C. Schatz,Ronglai Shen,Britta Weigelt,Francisco Sanchez-Vega,Jorge S. Reis-Filho,Jaclyn F. Hechtman +20 more
TL;DR: The findings indicate that dual-driver mutations occur in a rare subset of CRC, often within the same tumor cells and across multiple tumor sites, and may be related to dose-dependent signaling within the mitogen-activated protein kinase pathway.
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Pathological Evaluation of Rectal Cancer Specimens Using Micro-Computed Tomography
Masao Yoshida,Emine Cesmecioglu,Canan Fırat,Hirotsugu Sakamoto,Alexei Teplov,Noboru Kawata,Peter Ntiamoah,Takashi Ohnishi,Kareem Ibrahim,Efsevia Vakiani,Julio Garcia-Aguilar,Meera Hameed,Jinru Shia,Yukako Yagi +13 more
TL;DR: Whole-block imaging using micro-computed tomography (micro-CT) allows the nondestructive reconstruction of a three-dimensional view of tissues, implying that WBI may be used for accurate pathological evaluation of patients with rectal cancer, but the clinical impact is unclear.
Total neoadjuvant chemotherapy to facilitate delivery and tolerance of systemic chemotherapy and response in locally advanced rectal cancer.
Andrea Cercek,Campbell S.D. Roxburgh,Paul Strombom,J. Joshua Smith,Larissa K. Temple,Garrett M. Nash,Jose G. Guillem,Philip B. Paty,Rona Yaeger,Zsofia K. Stadler,Neil H. Segal,Diane Lauren Reidy,Jinru Shia,Efsevia Vakiani,Abraham J. Wu,Christopher H. Crane,Marc J. Gollub,Julio Garcia-Aguilar,Leonard B. Saltz,Martin R. Weiser +19 more
TL;DR: The most common therapy for locally advanced (T3/4 or N+) rectal cancer (LARC) consists of preoperative chemoradiotherapy (chemoRT) followed by surgery and adjuvant chemotherapy.
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Fecal microbiota transplantation for refractory immune-checkpoint-inhibitor colitis.
Arielle Elkrief,Natalie Smith,John B. Slingerland,Nathaniel Aleynick,Melissa Lumish,Paul A Giardina,Jamie E. Chaft,Paul B. Chapman,Juliana Eng,Robert J. Motzer,Robin B. Mendelsohn,Marcel R.M. van den Brink,Jinru Shia,Susan DeWolf,Matthew D. Hellmann,Jonathan U. Peled,David Faleck +16 more
TL;DR: In this paper , the authors used whole metagenomic shotgun sequencing (WMS) to profile the faecal microbiota profiles from N = 18 patients with immune-related colitis and described their clinical experience of N = 5 patients treated with healthy donor fecal microbial transplantation (FMT).
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