Jinpeng Li
Wuhan University
35 Papers
32 Citations
Jinpeng Li is an academic researcher from Wuhan University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 12, co-authored 26 publications. Previous affiliations of Jinpeng Li include Kanazawa Medical University.
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Papers
Renal protective effects of empagliflozin via inhibition of EMT and aberrant glycolysis in proximal tubules
Jinpeng Li,Haijie Liu,Susumu Takagi,Kyoko Nitta,Munehiro Kitada,Swayam Prakash Srivastava,Yuta Takagaki,Keizo Kanasaki,Keizo Kanasaki,Daisuke Koya +9 more
TL;DR: Taken together, SGLT2 inhibitors exhibit renoprotective potential that is partially dependent on the inhibition of glucose reabsorption and subsequent aberrant glycolysis in kidney tubules.
SIRT3 deficiency leads to induction of abnormal glycolysis in diabetic kidney with fibrosis.
Swayam Prakash Srivastava,Jinpeng Li,Munehiro Kitada,Hiroki Fujita,Yuichiro Yamada,Julie E. Goodwin,Keizo Kanasaki,Daisuke Koya +7 more
TL;DR: The suppression of SIRT3 protein level in diabetic kidney, displays responsibility in fibrogenic programming associated with aberrant glycolysis and such abnormal glyCOlysis is the therapeutic target in diabetes associated-kidney fibrosis.
Inhibition of Dipeptidyl Peptidase-4 Accelerates Epithelial-Mesenchymal Transition and Breast Cancer Metastasis via the CXCL12/CXCR4/mTOR Axis.
Fan Yang,Yuta Takagaki,Yasuo Yoshitomi,Takayuki Ikeda,Jinpeng Li,Munehiro Kitada,Asako Kumagai,Emi Kawakita,Sen Shi,Keizo Kanasaki,Daisuke Koya +10 more
TL;DR: It is shown that inhibition of DPP-4 accelerates breast cancer metastasis via induction of CXCL12/CXCR4, which activates mTOR to promote epithelial-mesenchymal transition (EMT) in metastatic cancer cells.
Ipragliflozin improves mitochondrial abnormalities in renal tubules induced by a high-fat diet
Susumu Takagi,Jinpeng Li,Yuta Takagaki,Munehiro Kitada,Kyoko Nitta,Toshiyuki Takasu,Keizo Kanasaki,Daisuke Koya +7 more
TL;DR: Whether SGLT2 inhibition in mice fed with a high‐fat diet (HFD) improved mitochondrial morphology and restored mitochondrial biogenesis‐related molecules is investigated.
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Snail-inspired AFG/GelMA hydrogel accelerates diabetic wound healing via inflammatory cytokines suppression and macrophage polarization.
Zhipeng Zhou,Tuo Deng,Maixian Tao,Lisha Lin,Luyun Sun,Xuemei Song,Dongxiu Gao,Zhongjuan Wang,Jinpeng Li,Lan Luo,Lian Yang,Mingyi Wu +11 more
TL;DR: Wang et al. as discussed by the authors developed a double-network hydrogel biomaterial that composed of snail glycosaminoglycan (AFG) and methacrylated gelatin (GelMA), in which AFG is the main bioactive component of snail mucus and GelMA provides a scaffold mimicking the proteins in snail slime.
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