Jingyue Yang
Washington University in St. Louis
18 Papers
165 Citations
Jingyue Yang is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Shotgun lipidomics & Cardiolipin. The author has an hindex of 15, co-authored 18 publications. Previous affiliations of Jingyue Yang include University of Washington.
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Papers
Reversible high affinity inhibition of phosphofructokinase-1 by acyl-CoA: a mechanism integrating glycolytic flux with lipid metabolism.
TL;DR: It is demonstrated that fatty acyl-CoA modulates phosphofructokinase activity through both covalent and noncovalent interactions to regulate glycolytic flux and enzyme membrane localization via the branch point metabolic node that mediates lipid flux through anabolic and catabolic pathways.
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Functional lipidomics: the roles of specialized lipids and lipid–protein interactions in modulating neuronal function
TL;DR: The advances in the understanding of the types of lipids and phospholipases in the brain and the role of functional lipidomics in increasing the chemical understanding of complex neuronal processes are summarized.
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Dramatic Accumulation of Triglycerides and Precipitation of Cardiac Hemodynamic Dysfunction during Brief Caloric Restriction in Transgenic Myocardium Expressing Human Calcium-independent Phospholipase A2γ
David J. Mancuso,Xianlin Han,Christopher M. Jenkins,John J. Lehman,Nandakumar Sambandam,Harold F. Sims,Jingyue Yang,Wei Yan,Kui Yang,Karen G. Green,Dana R. Abendschein,Jeffrey E. Saffitz,Richard W. Gross +12 more
TL;DR: The participation of iPLA2γ in the remarkable lipid plasticity of myocardium, its role in generating signaling metabolites, and its prominent effects in modulating energy storage and utilization in myocardia in different metabolic contexts are identified.
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Sequential Ordered Fatty Acid α Oxidation and Δ9 Desaturation Are Major Determinants of Lipid Storage and Utilization in Differentiating Adipocytes
Xiong Su,Xianlin Han,Jingyue Yang,David J. Mancuso,Jeannie Chen,Perry E. Bickel,Richard W. Gross +6 more
TL;DR: The power of global lipidomics is exploited to identify the critical role of peroxisomal processing of fatty acids in adipocyte lipid storage and metabolism and 3T3-L1 differentiatin is identified.
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Dramatic Accumulation of Triglycerides and Precipitation of Cardiac Hemodynamic Dysfunction during Brief Caloric Restriction in Transgenic Myocardium Expressing Human
David J. Mancuso,Xianlin Han,Christopher M. Jenkins,John J. Lehman,Nandakumar Sambandam,Harold F. Sims,Jingyue Yang,Wei Yan,Kui Yang,Karen G. Green,Dana R. Abendschein,Jeffrey E. Saffitz,Richard W. Gross +12 more
- 01 Jan 2007
TL;DR: In this paper, the role of iPLA2γ in integrating lipid and energy metabolism was investigated in transgenic mice containing the α-myosin heavy chain promoter (αMHC) placed proximally to the human iPLA 2γ coding sequence that resulted in cardiac myocyte-restricted expression of the enzyme.
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