Hyperlipidemia with the characteristic of excessive blood lipid level is a risk factor for stroke, coronary heart disease, myocardial infarction, hypertension, impaired glucose tolerance, diabetes, sudden death, and so on. Therefore, we should pay more attention to the dangers of hyperlipidemia and look for natural lipid-lowering ingredients to prevent and relieve hyperlipidemia. In recent years, various studies have shown that active ingredients from marine foods exhibit obvious anti-hyperlipidemia activity, which have attracted more and more researches' attention. This paper shows that the regulatory mechanisms of lipid metabolism mainly include the cholesterol metabolism balance and the metabolism balance of triglyceride and fatty acid. This paper also summarizes active ingredients from marine foods with the role of treating or preventing hyperlipidemia, and relevant literature published in the past decades are reviewed. The active ingredients from marine foods are divided into polysaccharides, lipids, proteins, saponins, polyphenols and others, which are described in this article from the aspects of active ingredients, sources, models, efficacy and mechanisms. This paper may provide a valuable reference for the development of functional ingredients from marine foods with anti-hyperlipidemia activity.

The improvements of functional ingredients from marine foods in lipid metabolism

Apheresis has an important role in the management of two common complex lipid disorders associated with a high risk of premature atherosclerotic disease, familial hypercholesterolemia (FH) and Lp(a) hyperlipidemia. More often than not, these high risk patients will first present to their primary care provider prior to consulting with a lipidologist. Because of this, FH and Lp(a)-hyperlipidemia require more emphasis globally in the public domain as well as in the medical community. Appropriate and aggressive treatment regimens include a combination of dietary and pharmacologic interventions with regularly scheduled apheresis sessions. LDL apheresis is a critical intervention for the successful treatment of homozygous FH patients, heterozygous FH patients intolerant to conventional therapy, patients with an elevated Lp(a) level or those patients with progressive cardiovascular disease despite maximum medical therapy. Newly released European guidelines emphasize the importance of screening and treatment of e...

Role of apheresis in the management of familial hypercholesterolemia and elevated Lp(a) levels

[Study on the selective removal of plasma low-density lipoprotein and fibrinogen by degraded carrageenan].

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[Study on the selective removal of plasma low-density lipoprotein and fibrinogen by degraded carrageenan].