Jing Quan
Zhejiang University
10 Papers
43 Citations
Jing Quan is an academic researcher from Zhejiang University. The author has contributed to research in topics: Catalysis & Monomer. The author has an hindex of 4, co-authored 10 publications. Previous affiliations of Jing Quan include Donghua University.
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Papers
Controllable selective enzymatic synthesis of N-acyl and O-acylpropranolol vinyl esters and preparation of polymeric prodrug of propranolol
TL;DR: Controllable selective synthesis strategy of polymerizable N -acyl and O-acylpropranolol vinyl derivatives was developed by enzyme-catalyzed acylation of propranoll using divinyl dicarboxylates with different carbon chain length as acyl donor.
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Synthesis of polymeric prodrugs of chlorphenesin with saccharide branches by chemo-enzymatic regioselective strategy
Jing Quan,Qi Wu,Xianfu Lin +2 more
TL;DR: In this paper, a facile and regioselective enzymatic synthesis approach to prepare polymerizable lipophilic chlorphenesin vinyl esters was developed, where the influence of different organic solvents, enzyme sources, reaction time and the acylation reagent was investigated.
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Chemo-enzymatic synthesis and sustained release of optically active polymeric prodrugs of chlorphenesin
TL;DR: In vitro released studies showed that the cumulative released optically pure chlorphenesin from the polymeric prodrug (VADG) was from 19.3% to 34.5% in pH 1.2 after 7 days.
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Lipase-catalyzed regioselective synthesis of lipophilic inosine ester derivatives
TL;DR: The obtained 5′- O -acyl derivatives are more lipophilic than the parent inosine and thus suitable for potentially pharmaceutical application.
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Patent
Solvent-free system biological catalysis fast synthesis method for feruloylated glycerol
Jing Quan,Limin Zhu,Bo Jiang,Yan Zheng +3 more
- 03 Jan 2008
TL;DR: In this article, a biologically catalyzing solvent-free system for rapidly synthesizing ferulic acid glyceride was proposed, which consists of three steps: firstly, dissolving the ferulic acids and ethanol after reflux heating reation under catalysis of thionyl chloride, extracting sodium bicarbonate, removing ethyl ether, statically precipitating crystals, obtaining ferilic acid ethyl ester, and purifying, secondly, reacting the Ferulic acid and ethanol, and glycerin under the reaction of candida rugosa lipase of biocat
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