Jing Cui
Zhejiang University
10 Papers
85 Citations
Jing Cui is an academic researcher from Zhejiang University. The author has contributed to research in topics: IGFBP7 & DNA methylation. The author has an hindex of 6, co-authored 8 publications.
Chat about Author
Papers
IGFBP7 plays a potential tumor suppressor role against colorectal carcinogenesis with its expression associated with DNA hypomethylation of exon 1.
Wenjing Ruan,Jie Lin,Enping Xu,Fangying Xu,Yu Ma,Hong Deng,Qiong Huang,Bingjian Lv,Hu Hu,Jing Cui,Meijuan Di,Jiankang Dong,Maode Lai +12 more
TL;DR: It is clearly demonstrated that IGFBP7 plays a potential tumor suppressor role against colorectal carcinogenesis and its expression is associated with DNA hypomethylation of exon 1.
Reactivation of IGFBP7 by DNA demethylation inhibits human colon cancer cell growth in vitro.
TL;DR: The findings indicate that 5-aza-dC may have anticancer function for colon cancer and restoration of IGFBP7 may involve in the biological effects induced by 5-az-dD in colon cancer cell lines, and suggest that 5.aza- dC has clinical potential in the treatment of colorectal cancer.
37
Identification of a novel VNTR polymorphism in C6orf37 and its association with colorectal cancer risk in Chinese population.
TL;DR: A novel VNTR polymorphism in C6orf37 exists in Chinese population and is not associated with colorectal cancer risk.
9
Early B cell factor 4 modulates FAS-mediated apoptosis and promotes cytotoxic function in human immune cells
Satoshi Kubo,Rhea Kataria,Yi-Chuan Yao,Justin Q Gabrielski,Lixin Zheng,Tovah E. Markowitz,Waipan Chan,Jian Song,Arun K. Boddapati,Keita Saeki,Björn Häupl,Ann Y. Park,Yan H Cheng,Jing Cui,Thomas Oellerich,Michael J. Lenardo +15 more
TL;DR: The identified EBF4, a little-studied member of the early B cell factor (EBF) family of transcription factors, in a whole-genome CRISPR screen for regulators of Fas/APO-1/CD95-mediated T cell death, and its presence in the Fas signaling complex impairs caspase-8 cleavage and apoptosis.
8
Human G Protein-Coupled Receptor 15 mutations associated with inflammatory bowel disease.
TL;DR: In this paper , G Protein-Coupled Receptor 15 (GPR15) is found in the gastrointestinal basal epithelial region and presumably guides GPR15+ T cells to that location.