Jin Wei
University of South Florida
28 Papers
75 Citations
Jin Wei is an academic researcher from University of South Florida. The author has contributed to research in topics: Macula densa & Tubuloglomerular feedback. The author has an hindex of 11, co-authored 28 publications.
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Papers
Macula Densa SGLT1-NOS1-Tubuloglomerular Feedback Pathway, a New Mechanism for Glomerular Hyperfiltration during Hyperglycemia.
Jie Zhang,Jin Wei,Shan Jiang,Lan Xu,Lei Wang,Feng Cheng,Jacentha Buggs,Hermann Koepsell,Volker Vallon,Ruisheng Liu +9 more
TL;DR: A novel mechanism of acute hyperglycemia-inducedhyperfiltration is identified wherein increases in luminal glucose at the macula densa upregulate the expression and activity of NOS1 via SGLT1, blunting the TGF response and promoting glomerular hyperfiltration.
84
Role of Kidneys in Sex Differences in Angiotensin II-Induced Hypertension.
Lei Wang,Ximing Wang,Helena Y. Qu,Shan Jiang,Jie Zhang,Liying Fu,Jacentha Buggs,Bo Pang,Jin Wei,Ruisheng Liu +9 more
TL;DR: It is found that same-sex–KTX mice still exhibited sex differences in Ang II–dependent hypertension, but the cross-sex KTXs exhibited more robust inflammatory responses reflected by higher expression of IL-6, TNF&agr;, and KC (keratinocyte-derived chemokine) than same- Sex differences in blood pressure regulation are found.
27
Shear stress blunts tubuloglomerular feedback partially mediated by primary cilia and nitric oxide at the macula densa.
Lei Wang,Chunyu Shen,Haifeng Liu,Shaohui Wang,Xinshan Chen,Richard J. Roman,Luis A. Juncos,Yan Lu,Jin Wei,Jie Zhang,Kay-Pong Yip,Ruisheng Liu +11 more
TL;DR: Shear stress stimulates primary cilia on the macula densa to enhance NO generation and inhibit TGF responsiveness and the effects of raising perfusate viscosity with dextran on tubular hydraulic pressure were minimized by reducing the outflow resistance to avoid stretching of tubular cells.
22
Role of intratubular pressure during the ischemic phase in acute kidney injury.
Jin Wei,Jiangping Song,Jiangping Song,Shan Jiang,Shan Jiang,Gensheng Zhang,Gensheng Zhang,Donald E. Wheeler,Jie Zhang,Shaohui Wang,En Yin Lai,Lei Wang,Jacentha Buggs,Ruisheng Liu +13 more
TL;DR: It is found that higher Pt during the ischemic phase promoted the development of AKI, while lower Pt protected from kidney injury, and may be a potential target for treatment ofAKI.
22
High-Protein Diet-Induced Glomerular Hyperfiltration Is Dependent on Neuronal Nitric Oxide Synthase β in the Macula Densa via Tubuloglomerular Feedback Response.
TL;DR: It is demonstrated that high-protein diet-induced glomerular hyperfiltration is dependent on neuronal NO synthase β in the macula densa via TGF response.
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